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Smooth Muscle Cells

All articles tagged with #smooth muscle cells

Targeting Mid-Old Cells: Unlocking Anti-Aging Interventions for the Elderly

Originally Published 2 years ago — by Nature.com

Accumulation of senescent cells in tissues is a major contributor to aging and organ dysfunction. However, a subset of cells in an intermediate stage of cellular senescence, termed "mid-old cells," has been identified. These mid-old cells exhibit distinct gene expression patterns and functional characteristics compared to young and old cells. They are associated with specific inflammation markers and have the capacity to respond to external stimuli. Mid-old cells are found in elderly tissues, particularly in fibroblasts and smooth muscle cells, and contribute to age-related microenvironments. The presence of mid-old cells suggests a potential target for anti-aging interventions in the elderly.

health health aging fibroblasts health inflammation senescent-cells smooth-muscle-cells

Unveiling the Secrets of the Nation's Leading Killer: Coronary Artery Disease

Originally Published 2 years ago — by Medical Xpress

Researchers at the University of Virginia Health have identified critical biological processes that contribute to coronary artery disease, the leading cause of death in the United States. The study focused on smooth muscle cells that line blood vessels and found that problems with metabolic pathways, specifically how the cells use nitrogen and glycogen, may contribute to the development and progression of the disease. The discovery provides new targets for potential therapies and interventions to treat and prevent coronary artery disease.

health health biological-processes coronary-artery-disease health metabolic-pathways plaque-buildup smooth-muscle-cells