Tag

Metabolic Pathways

All articles tagged with #metabolic pathways

health2 years ago•3 min saved

Unveiling the Secrets of the Nation's Leading Killer: Coronary Artery Disease

Researchers at the University of Virginia Health have identified critical biological processes that contribute to coronary artery disease, the leading cause of death in the United States. The study focused on smooth muscle cells that line blood vessels and found that problems with metabolic pathways, specifically how the cells use nitrogen and glycogen, may contribute to the development and progression of the disease. The discovery provides new targets for potential therapies and interventions to treat and prevent coronary artery disease.

via Medical Xpress|

#biological-processes #coronary-artery-disease #health

health2 years ago•7 min saved

Uncovering the Link Between Microbiome and Autism Spectrum Disorder.

A new study using a unique computational approach has identified a distinctive microbial signature in autistic individuals that could help distinguish them from neurotypical individuals. The study also underscores the importance of long-term studies that involve interventions to provide insight into the cause-and-effect relationship between the microbiome and autism. The study's comprehensive approach may also prove instrumental in investigating other complex conditions where the microbiome may play a role, such as depression, Parkinson's, and cancer.

via Neuroscience News|

#autism #computational-approach #health

neuroscience2 years ago•4 min saved

The Importance of Eye Color Genes for Retinal Health

The Kynurenine pathway, responsible for eye pigment formation, also plays a crucial role in maintaining retinal health under stress conditions, according to a study by researchers from the Max Planck Institute of Molecular Cell Biology and Genetics. The study used Drosophila melanogaster as a model system to unravel the role of individual metabolites in retinal health and found that the balance between toxic and protective metabolites, such as 3-hydroxykynurenine and Kynurenic Acid, respectively, influences the degree of retinal degeneration. The researchers suggest that therapeutic strategies for neurodegenerative conditions should take into account the ratio and location of Kynurenine pathway metabolites.

via Neuroscience News|

#drosophila #genetics #kynurenine-pathway

health2 years ago•3 min saved

The Crucial Role of Eye Color Genes in Retinal Health

A study by researchers from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, has found that genes responsible for eye color pigmentation also play a critical role in maintaining retinal health. The study focused on the kynurenine pathway, a metabolic pathway that regulates various biological processes, and found that the balance between toxic and protective metabolites within the pathway influences the health of the retina. The researchers suggest that therapeutic strategies for neurodegenerative conditions should take into account the ratio of various metabolites and their specific sites of accumulation and activity within the pathway.

via Medical Xpress|

#eye-health #gene-mutations #health