All articles tagged with #single cell sequencing
EMBL scientists developed SDR-seq, a new single-cell DNA-RNA sequencing tool that simultaneously studies both genetic variations and gene expression, especially in non-coding regions linked to diseases, enabling faster and more accurate disease connection discoveries.
The article discusses the development of the Biodiversity Cell Atlas, a comprehensive mapping of the tree of life at cellular resolution, utilizing advanced single-cell sequencing and multi-omic techniques to understand cellular diversity and evolution across species.
The study investigates how dysregulation of myeloid progenitors contributes to the formation of immunosuppressive macrophages in tumors, using single-cell sequencing techniques to analyze the tumor microenvironment and identify potential therapeutic targets.
Researchers at the Pasteur Institute in France have created a comprehensive transcriptomic atlas of the mouse cochlea using single-cell sequencing, identifying nearly all cochlear cell types and discovering three previously unknown cell types. The study sheds light on the molecular basis of the tonotopic gradient of the basilar membrane's biophysical characteristics and reveals the expression of deafness genes in several cochlear cell types. The atlas will be useful for finding overlooked cochlear cells affected by particular deficits and may reveal causal sources for deafness of unknown origin.