Tag

Cochlea

All articles tagged with #cochlea

health5 days ago

Revolutionary Ear Technology Paves the Way for Hearing Loss Solutions

Researchers at Rockefeller University have successfully kept a segment of the mammalian cochlea alive outside the body, enabling detailed study of its active sound amplification process. This breakthrough confirms that mammals rely on a universal biophysical principle involving Hopf bifurcation for amplifying faint sounds, paving the way for new treatments for sensorineural hearing loss by understanding and potentially repairing hair cell damage.

medical-science2 years ago

Revolutionary Discovery: A New Path to Cure Deafness

Researchers have discovered a new pathway into the inner ear, known as the cochlear aqueduct, which allows for the delivery of drugs directly to the cochlea. By utilizing the natural flow of fluids in the brain, scientists successfully restored hearing in deaf mice by delivering a gene therapy through this pathway. The findings suggest that cerebrospinal fluid transport could be a potential route for gene therapy to restore hearing in humans, offering hope for the millions of people worldwide who suffer from hearing loss.

science2 years ago

New cell types and molecular features discovered in cochlea cell atlas through single-cell sequencing.

Researchers at the Pasteur Institute in France have created a comprehensive transcriptomic atlas of the mouse cochlea using single-cell sequencing, identifying nearly all cochlear cell types and discovering three previously unknown cell types. The study sheds light on the molecular basis of the tonotopic gradient of the basilar membrane's biophysical characteristics and reveals the expression of deafness genes in several cochlear cell types. The atlas will be useful for finding overlooked cochlear cells affected by particular deficits and may reveal causal sources for deafness of unknown origin.