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Psychedelic Therapy

All articles tagged with #psychedelic therapy

health7 days ago•7 min saved

One Short DMT Dose Sparks Lasting Depression Relief in Phase IIa Trial

A Phase IIa randomized trial found that a single 21.5 mg IV dose of DMT, producing a ~25-minute psychedelic experience, yielded rapid and durable antidepressant effects in adults with moderate-to-severe treatment-resistant depression—MADRS scores dropped more than placebo within one week and effects persisted up to six months for some participants; efficacy correlated with the intensity of the peak experience, and the brief session could be more cost-effective and easier to implement than longer psychedelic therapies, though larger trials are needed and use is restricted to controlled clinical settings with professional support.

via Neuroscience News|

#depression #dmt #health

health8 days ago•17 min saved

Small DMT Trial Signals Potential Depression Treatment

A small UK Phase IIa randomized, placebo-controlled trial found that a single dose of DMT with psychotherapy significantly reduced depressive symptoms for up to three months (some participants up to six); 47% reached remission at three months. DMT appeared safe and well tolerated, but the study's small size means larger, longer trials are needed before it could become a standard depression treatment.

via Gizmodo|

#depression #dmt #health

health1 month ago•10 min saved

Debate Sparks Over NHS Using Magic Mushrooms for Mental Health Treatment

The article discusses the potential use of psilocybin, the active compound in magic mushrooms, as a treatment for mental health conditions like depression and PTSD, highlighting promising research, regulatory challenges, and differing opinions on safety and efficacy.

via BBC|

#depression #health #magic-mushrooms

science1 month ago•4 min saved

2025 Neuroscience Highlights: Key Discoveries and Future Predictions

In 2025, significant advancements in consciousness research included exploring the possibility of universal consciousness before the Big Bang, recognizing consciousness as more widespread and ancient across species, breakthroughs in psychedelic therapy and altered states, progress in competing theories of consciousness, and increased attention to near-death experiences and their psychological impact, marking a shift towards viewing consciousness as a tangible scientific frontier.

via The Debrief|

#consciousness #near-death-experiences #neuroscience

health4 months ago•3 min saved

Revolutionary Psychedelic Approaches Offer New Hope for Mental Health

Scientists at UCSF are exploring a pharmaceutical form of LSD, MM120, as a potential treatment for generalized anxiety disorder (GAD), showing promising results in reducing symptoms by promoting neuroplasticity and brain communication, with manageable side effects, offering hope for those unresponsive to traditional medications.

via ScienceDaily|

#anxiety #gad #health

health4 months ago•3 min saved

New Therapy Shows Promise in Reducing Anxiety for Millions

UCSF is exploring a novel psychedelic drug, MM120, derived from LSD, which has shown promising results in reducing symptoms of generalized anxiety disorder by promoting neuroplasticity and improving brain communication, potentially offering a more effective treatment than current medications, despite some mild side effects.

via UC San Francisco|

#anxiety #clinical-trials #generalized-anxiety-disorder

health5 months ago•4 min saved

Single LSD Dose May Reduce Anxiety, Study Finds

A new study shows that a single high dose of LSD (MM120) can significantly reduce anxiety and depression in adults with generalized anxiety disorder, with effects lasting up to 12 weeks, though environmental factors may also influence outcomes. The research supports the potential of psychedelics as future psychiatric treatments, pending further studies and FDA approval.

via NPR|

#anxiety #gad #health

health5 months ago•3 min saved

LSD may offer long-term anxiety and depression relief after a single dose

Research suggests that a single dose of MM120, an LSD formulation, may significantly reduce symptoms of generalized anxiety disorder with effects lasting up to three months, though further studies are needed to confirm safety and efficacy.

via ABC News|

#anxiety #clinical-trial #health

business6 months ago•4 min saved

AbbVie Acquires Gilgamesh's Psychedelic Depression Therapy in $1.2B Deal

AbbVie is acquiring Gilgamesh Pharmaceuticals' investigational drug bretisilocin, a promising psychedelic therapy in Phase 2 trials for major depressive disorder, aiming to expand its psychiatric treatment portfolio. The drug has shown significant antidepressant effects with a shorter psychoactive duration, and the deal includes up to $1.2 billion in potential payments. This move underscores AbbVie's commitment to innovative mental health treatments.

via AbbVie News Center|

#abbvie #bretisilocin #business

health8 months ago•1 min saved

Psychedelic Treatments Demonstrate Rapid Effectiveness Against Depression

A mid-stage trial of Beckley Psytech's psychedelic therapy for treatment-resistant depression shows significant symptom reduction, boosting prospects for approval amid a shifting regulatory landscape for psychedelic drugs.

via STAT|

#beckley-psytech #clinical-trial #depression

health8 months ago•4 min saved

Single Dose of Magic Mushrooms Offers Long-Term Depression Relief

A study presented at Psychedelic Science 2025 suggests that a single dose of psilocybin, the active compound in magic mushrooms, can provide depression relief lasting up to five years, with many participants experiencing remission and improved mental health, highlighting the potential of psychedelic treatments for depression.

via Yahoo|

#depression #health #long-term-effects

health8 months ago•4 min saved

Single Dose of Psychedelic Compound Provides Long-Term Depression Relief for Cancer Patients

A study reveals that a single dose of psilocybin can alleviate depression for at least five years, with 67% of participants remaining in remission, suggesting long-lasting benefits of psychedelic therapy for severe depression, though further research is needed due to small sample sizes.

via Live Science|

#depression #health #long-term-effects

health8 months ago•7 min saved

Single-dose psilocybin may cut alcohol use

A small study found that a single high dose of psilocybin, combined with psychological support, can significantly reduce alcohol consumption and cravings in individuals with severe alcohol use disorder, with effects lasting at least 12 weeks, though larger controlled studies are needed to confirm these findings.

via PsyPost|

#alcohol-use-disorder #clinical-trial #health

health8 months ago•4 min saved

Doctor Tests Psilocybin as Potential IBS Treatment

Dr. Erin Mauney is conducting pioneering research on using psilocybin, the active compound in magic mushrooms, to treat irritable bowel syndrome (IBS), especially in patients unresponsive to traditional treatments. Her approach aims to reset the mind-body connection and address psychological trauma that may contribute to physical symptoms, with early promising results. The study involves guided therapy sessions and brain imaging to explore how psychedelics might help patients better interpret internal bodily signals, offering hope for a holistic treatment option for chronic digestive issues.

via Study Finds|

#gut-brain-connection #health #ibs

health1 year ago•1 min saved

FDA Panel Rejects MDMA Therapy for PTSD

An FDA advisory panel voted 9-2 against approving MDMA for PTSD treatment, citing concerns over clinical trial methodology and therapist oversight, and 10-1 against the benefits outweighing the risks under the proposed REMS program.

via STAT|

#clinical-trials #fda #health