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Primec

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"Promising ALS Drug Trials and Treatment Strategies for 2024"

Originally Published 1 year ago — by Benzinga

NeuroSense's ALS drug candidate, PrimeC, showed promising results in a recent phase 2b trial, with a 29.2% decline in disease progression and a 13.3% slowing of respiratory function loss. The drug consists of two FDA-approved drugs targeting multiple ALS mechanisms. Participants showed strong interest in continuing PrimeC treatment, and the company is expecting major milestones in 2024, including results from a collaboration with Biogen and phase 3 trial initiation. If successful, PrimeC could offer a significant clinical benefit to ALS patients, potentially leading to an expedited regulatory pathway for market approval.

health health-pharmaceuticals als biogen health-pharmaceuticals neurosense phase-2b-trial primec

"PrimeC: A Promising Breakthrough in ALS Treatment, Enhancing Survival of Motor Neurons"

Originally Published 2 years ago — by ALS News Today

NeuroSense Therapeutics' investigational therapy, PrimeC, has shown promising results in a lab study by significantly boosting the survival of patient-derived motor neurons in amyotrophic lateral sclerosis (ALS) to levels similar to healthy controls. PrimeC is a fixed-dose combination of the antibiotic ciprofloxacin and the anti-inflammatory celecoxib, targeting inflammation and other mechanisms that damage motor neurons. The therapy is currently being evaluated in a Phase 2b clinical trial, with results expected later this year.

health medical-research als clinical-trial medical-research motor-neurons neurosense-therapeutics primec