Tag

Pcsk9 Inhibitors

All articles tagged with #pcsk9 inhibitors

health-and-medicine4 hours ago•15 min saved

Cholesterol drug cuts first cardiovascular events by 31% in diabetics without artery disease

A Mass General Brigham study finds the PCSK9 inhibitor evolocumab, added to standard therapy, reduces the risk of a first major cardiovascular event by 31% over ~5 years in high‑risk diabetics without diagnosed atherosclerosis, with about a 51% drop in LDL‑C. Safety was similar to placebo, suggesting earlier intensive cholesterol lowering may prevent heart attacks and strokes in patients without established artery disease; results were presented at the ACC and published in JAMA.

via ScienceDaily|

#cardiovascular-disease #diabetes #evolocumab

health6 months ago•3 min saved

Dr. Roach: PCSK9i Drugs as Viable Statin Alternatives

Dr. Roach discusses the effectiveness of PCSK9 inhibitors as alternatives to statins for cholesterol management, especially in those who cannot tolerate statins, and provides insights on treatments for long-term COVID-19 related loss of smell and prurigo nodularis, emphasizing various therapeutic options.

via The Detroit News|

#cholesterol #covid-19-loss-of-smell #health

health2 years ago•4 min saved

Breakthrough Vaccine Lowers Cholesterol, Revolutionizing Heart Health

Researchers at The University of New Mexico School of Medicine have developed a vaccine that could lower "bad" LDL cholesterol, which can lead to heart disease and stroke. The vaccine, which targets the PCSK9 protein, has been shown to reduce cholesterol levels by up to 30% in animal studies. The researchers hope to move into vaccine manufacturing and clinical trials with humans in the next few years, with the goal of creating a pure, safe, and affordable vaccine that could have a global impact on heart disease.

via Medical Xpress|

#cholesterol #health #heart-health

health2 years ago•2 min saved

Potential Lung Risks Found in New Cholesterol Medications, Reveals Global Study

A groundbreaking global study analyzing genetic data from 340,000 UK Biobank participants has found that PCSK9 inhibitors, a new class of cholesterol-lowering drugs, could potentially impair lung function. The study also revealed correlations between statins and higher BMI, body fat, and reduced testosterone, while unexpectedly noting an increase in hippocampus brain volume that may lower dementia and depression risks. Further research is needed to understand the long-term effects of these medications and to assess their safety and potential benefits.

via SciTechDaily|

#cholesterol-drugs #genetic-analysis #health

healthcare2 years ago•7 min saved

Managing Cardiovascular Disease Through Cholesterol Reduction.

Patients with cardiovascular diseases often have much higher LDL cholesterol levels than recommended in the guidelines, and only a minority of patients receive combination therapy, and PCSK9 inhibitors are rarely prescribed. The recent SANTORINI study once again highlights the need for the intensive application of lipid-lowering drugs. The DA-VINCI study showed a massive discrepancy between the target levels of LDL cholesterol stipulated in the European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guidelines and the levels achieved in clinical practice.

via Medscape|

#cardiovascular-disease #cholesterol #guidelines