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P Tau217

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Blood biomarker could forecast dementia risk decades ahead in older women.
health3 hours ago

Blood biomarker could forecast dementia risk decades ahead in older women.

A UC San Diego-led study of 2,766 women aged 65–79 from the Women’s Health Initiative Memory Study found that higher blood levels of the biomarker p-tau217 are strongly linked to future dementia and mild cognitive impairment, suggesting a simple blood test could identify those at greatest risk up to 25 years before symptoms. While promising for early prevention and monitoring, blood-based testing for Alzheimer's is not yet recommended for routine screening, and results may not apply to men or younger populations.

via Fox News|
#alzheimers-disease#biomarkers#blood-test
Blood Biomarker Could Flag Dementia Risk Decades Ahead in Women
health6 hours ago

Blood Biomarker Could Flag Dementia Risk Decades Ahead in Women

A UC San Diego study of over 2,500 women found that higher blood levels of the biomarker p-tau217 can predict future dementia risk up to 25 years before symptoms, with stronger links in women over 70, those with Alzheimer’s genetic risk, or on estrogen-progestin therapy; while promising, more studies are needed and it isn’t yet ready for routine clinical use, but could guide prevention trials.

via Gizmodo|
#alzheimers-disease#biomarker#blood-test
Shared Trait Found in Newborns and Alzheimer’s Patients
science8 months ago

Shared Trait Found in Newborns and Alzheimer’s Patients

A recent study reveals that both newborns and Alzheimer's patients have elevated levels of the brain protein p-tau217, which plays different roles in each group—supporting healthy brain development in infants and indicating neurodegeneration in Alzheimer's. The findings suggest that understanding how the healthy brain manages tau could lead to new treatments for Alzheimer's disease.

via SciTechDaily|
#alzheimers#biomarker#brain-development
Alzheimer’s-Linked Protein Detected in Newborns, Offering New Hope
health8 months ago

Alzheimer’s-Linked Protein Detected in Newborns, Offering New Hope

A study found that healthy newborns have higher levels of the Alzheimer’s-linked protein p-tau217 than dementia patients, suggesting this protein plays a crucial role in early brain development rather than solely causing neurodegeneration. This discovery challenges existing beliefs about tau proteins and could lead to new approaches in treating or preventing Alzheimer’s disease by understanding how infant brains manage high tau levels safely.

via The Conversation|
#alzheimers#brain-development#dementia
"Breakthrough Blood Test for Alzheimer's Shows Promise in Early Detection"
health2 years ago

"Breakthrough Blood Test for Alzheimer's Shows Promise in Early Detection"

A new study suggests that a blood test screening for Alzheimer’s disease using a protein called p-tau217 could be highly accurate in identifying key biomarkers of the disease, even before symptoms appear. The test, which is commercially available for research use, showed up to 96% accuracy in identifying elevated levels of beta amyloid and up to 97% accuracy in identifying tau, making it comparable to advanced testing methods like brain scans and spinal taps. This development could lead to improved patient management, timely access to therapies, and more cost-effective and accessible diagnostic options for the growing number of people at risk for Alzheimer's disease.

via CNN|
#alzheimers-disease#blood-test#cognitive-impairment