Blood biomarker could forecast dementia risk decades ahead in older women.

TL;DR Summary
A UC San Diego-led study of 2,766 women aged 65–79 from the Women’s Health Initiative Memory Study found that higher blood levels of the biomarker p-tau217 are strongly linked to future dementia and mild cognitive impairment, suggesting a simple blood test could identify those at greatest risk up to 25 years before symptoms. While promising for early prevention and monitoring, blood-based testing for Alzheimer's is not yet recommended for routine screening, and results may not apply to men or younger populations.
- Lurking dementia risk exposed by breakthrough test 25 years before symptoms Fox News
- Blood Test Predicts Dementia in Women as Many as 25 Years Before Symptoms Begin UC San Diego Today
- Scientists Find Alzheimer’s Clues Hidden in the Shape of Blood Proteins SciTechDaily
- Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification PNAS
- Blood protein structure changes may reveal early signs of Alzheimer’s News-Medical
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