Tag

Nanobodies

All articles tagged with #nanobodies

biology19 days ago•8 min saved

Tiny llama nanobodies lock coronavirus spike to block infection across variants

Researchers identified llama-derived single-domain antibodies (nanobodies) that bind a conserved base region (S2) of the coronavirus spike and act like a clamp, locking the spike in its original shape and preventing the conformational changes needed for cell entry. In animal tests these nanobodies provided strong protection at low doses and showed a high barrier to viral escape, neutralizing a broad range of SARS-related coronaviruses and offering potential for long-lasting antiviral therapies resilient to future variants.

via SciTechDaily|

#biology #broad-neutralization #coronavirus

health3 months ago•2 min saved

Camelid Antibodies Offer New Hope for Alzheimer's Treatment

A new study suggests that nanobodies, small antibody-like proteins found in camelids like alpacas, could be developed into treatments for brain disorders such as Alzheimer's, offering potential advantages over traditional antibodies due to their size and ability to passively enter the brain, though further safety and efficacy testing is needed before clinical trials.

via Good News Network|

#alzheimers #antibodies #brain-disorders

health3 months ago•5 min saved

Revolutionary Next-Gen Antivenom Offers New Hope for Snakebite Victims

Scientists at DTU have developed a new broad-spectrum nanobody-based antivenom that could revolutionize snakebite treatment, especially in Africa, by targeting multiple snake species with a safer, more stable, and cost-effective solution, though human trials are still needed.

via Times of India|

#antivenom #dtu-bioengineering #global-health

healthtech2 years ago•5 min saved

Cutting-Edge Air Monitor Instantly Identifies COVID-19, Flu, RSV, and More

Researchers at Washington University in St. Louis have developed a proof-of-concept air quality monitor that can detect live SARS-CoV-2 virus in indoor environments in real-time. The monitor uses a biosensor made with nanobodies and operates based on wet cyclone technology. It can provide results within 5 minutes and has the potential to detect other respiratory viruses such as flu and RSV. The device could be used in hospitals, schools, and public places to enhance safety measures and monitor the presence of viruses in the air.

via SciTechDaily|

#air-quality-monitor #covid-19 #healthtech

health2 years ago•2 min saved

Nanopores for Early Disease Detection

Researchers at Aarhus University and Groningen University have developed ClyA nanopores with nanobodies attached to them, which can detect specific proteins in complex biological fluids like blood without chemical labeling. The nanopores remained highly accurate and sensitive even when tested with complex samples like blood. This breakthrough could revolutionize medical diagnostics and lead to earlier interventions, improved treatment outcomes, and overall improved healthcare.

via Phys.org|

#disease-detection #health #medical-diagnostics