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Mass General Cancer Center

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"Promising Results: Innovative Treatments Shrink Aggressive Brain Tumors in Clinical Trials"

Originally Published 1 year ago — by The Boston Globe

Featured image for "Promising Results: Innovative Treatments Shrink Aggressive Brain Tumors in Clinical Trials"
Source: The Boston Globe

A new form of CAR-T cell therapy, called CAR-TEAM, has shown promising results in shrinking aggressive glioblastoma brain tumors in a small clinical trial at Mass General Cancer Center. Three patients experienced significant tumor shrinkage after a single infusion, with one patient's tumor remaining nearly undetectable during the follow-up period. While two patients saw tumor regrowth within six months, researchers are hopeful about the early signs of efficacy and plan to enhance the treatment's durability by combining it with chemotherapy.

"Living Cell Therapy Shows Dramatic Progress Against Glioblastoma Tumors"

Originally Published 1 year ago — by WCVB Boston

Featured image for "Living Cell Therapy Shows Dramatic Progress Against Glioblastoma Tumors"
Source: WCVB Boston

A phase 1 clinical trial at the Mass General Cancer Center has shown promising early results in treating glioblastoma, a lethal brain cancer, with a novel CAR-T cell therapy. The treatment, which involves specially engineered T-cells injected directly into the fluid around the brain, has demonstrated dramatic and rapid tumor reduction in early trials. While more research is needed, the initial findings provide hope for improved treatment options for this aggressive form of cancer.