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Fecal Microbiota Transplant

All articles tagged with #fecal microbiota transplant

science5 hours ago

Gut Microbes Brew Alcohol: Donor Stool Transplants Offer Hope for Auto-Brewery Syndrome

Researchers detail auto-brewery syndrome (ABS), a rare condition where gut microbes convert carbohydrates into ethanol, causing involuntary intoxication. A Nature Microbiology study identifies overabundant bacteria (notably E. coli and Klebsiella) and fermentation pathways that drive ethanol production during flares, while fungal overgrowth is less central than once thought. The work also documents a successful treatment: a donor stool–derived capsule fecal microbiota transplant that produced long-lasting remission in at least one patient, implying a diagnostic framework and the potential for microbiome-directed therapies to manage ABS.

health1 year ago

"FDA Issues Warning on 'Gut-Boosting' Pills Containing Donor Fecal Matter"

The FDA has issued a warning against the use of at-home fecal microbiota transplant (FMT) products, such as those offered by Human Microbes, due to significant safety concerns and lack of regulation. While FMT has shown promise in treating certain infections, the use of unregulated products containing other people's fecal matter poses serious risks, including potentially deadly infections. Experts emphasize the importance of proper screening and regulation in FMT products to ensure safety and efficacy.

health1 year ago

"Fecal Microbiota Transplant Shows Promise in Alleviating Parkinson's Symptoms"

A small clinical trial found that fecal microbiota transplant, a procedure that replaces a person’s gut bacteria with bacteria from a healthy donor, may help ease motor symptoms of Parkinson’s disease. The study showed that patients with mild to moderate Parkinson’s who underwent the transplant experienced improved motor symptoms and less severe constipation. While the findings are promising, larger studies are needed to confirm the results and explore the potential of this therapeutic approach in patients at various disease stages.

health2 years ago

FDA approves groundbreaking fecal transplant pill for gut health.

The FDA has approved the first pill made from donated human feces, called Vowst, as a preventive treatment for recurrent infections with the bacterium Clostridioides difficile. The pill contains live bacteria and is taken orally, unlike the previously approved enema-based treatment. Antibiotics can disrupt the balance of bacteria in the gut, leading to C. diff infections. Fecal microbiota products offer a new way to prevent recurrent C. diff by replenishing the gut microbiome. The Vowst treatment regimen involves taking four capsules once a day for three days in a row, starting two to four days after finishing a course of antibiotics for C. diff.