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Dna Repair

All articles tagged with #dna repair

Greenland sharks may live for centuries thanks to enhanced DNA repair
science1 month ago

Greenland sharks may live for centuries thanks to enhanced DNA repair

Scientists estimate Greenland sharks can live around 400–500 years and have found that eye tissue remains capable of vision in old age due to heightened DNA repair activity. Genome analysis reveals expanded DNA repair genes and a unique p53 insertion, and their hearts tolerate age-related damage. Researchers caution that this does not imply immediate human health applications or any antiaging use for shark products.

Bowhead whales' DNA repair mechanisms may unlock secrets to longevity
science3 months ago

Bowhead whales' DNA repair mechanisms may unlock secrets to longevity

Scientists studying bowhead whales have identified a protein called CIRBP that helps repair DNA and may contribute to the whale's extraordinary lifespan and resistance to cancer. This discovery could lead to new ways to extend human life and prevent age-related diseases, possibly through lifestyle changes like cold exposure or new therapies targeting DNA repair mechanisms.

Bowhead Whales' Longevity: Insights from DNA Repair and CIRBP Protein
science3 months ago

Bowhead Whales' Longevity: Insights from DNA Repair and CIRBP Protein

Research shows that bowhead whales have enhanced DNA repair mechanisms, particularly in double-strand break repair, and high levels of the protein CIRBP, which contribute to their exceptional lifespan and cancer resistance despite their large size and long life. These findings suggest that improved genome maintenance, rather than increased apoptosis, underpins their longevity and resistance to age-related diseases.

Bowhead Whales' Longevity Offers Clues to Slowing Aging
science3 months ago

Bowhead Whales' Longevity Offers Clues to Slowing Aging

Scientists studying bowhead whales, which can live over 200 years, have identified enhanced DNA repair mechanisms involving the protein CIRBP, which is triggered by cold exposure. These mechanisms may contribute to their exceptional longevity and low cancer rates. Experiments suggest boosting CIRBP in humans could improve DNA repair and potentially slow aging, with ongoing research exploring this possibility.