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Braincircuit

All articles tagged with #braincircuit

"Breakthrough Discovery Paves Way for Potential Cure in Panic Disorder Treatment"

Originally Published 2 years ago — by Neuroscience News

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Source: Neuroscience News

Researchers at the Salk Institute have identified a brain circuit involving PACAP-expressing neurons in the parabrachial nucleus that is linked to panic disorder. This discovery suggests new potential targets for treatment, as inhibiting PACAP signaling reduced panic symptoms in a mouse model. The findings, which diverge from traditional treatments focusing on the brain's serotonin system, could lead to more effective panic disorder therapeutics and further understanding of the condition's distinct nature from other anxiety disorders. The research was supported by the National Institutes of Mental Health and the Simons Foundation and will be published in Nature Neuroscience.

"Unlocking the Secrets of Male Desire: Brain Circuit Discovery in Mice"

Originally Published 2 years ago — by ScienceAlert

Featured image for "Unlocking the Secrets of Male Desire: Brain Circuit Discovery in Mice"
Source: ScienceAlert

Researchers at Stanford University have identified a specific brain circuit in male mice that controls sexual recognition, libido, mating behavior, and pleasure. This circuit involves neurons in the bed nucleus of the stria terminalis (BNST) producing Substance P, which connects to neurons with Substance P receptors in the preoptic hypothalamus. Stimulating these neurons can trigger mating behavior and even override the refractory period in male mice. The findings suggest that similar brain circuits may exist in humans and could lead to the development of drugs to manage sexual drive. The study's insights into this fundamental brain circuitry could have broader implications for understanding mammalian, including human, sexuality.