All articles tagged with #blood proteins
Originally Published 3 months ago — by Financial Times
Researchers have identified changes in multiple blood proteins that could serve as early clues for cancer detection, potentially leading to improved screening and diagnosis methods.
Originally Published 1 year ago — by South China Morning Post
Chinese scientists have used a massive database and AI to identify proteins linked to the risk of developing dementia, creating a predictive model to assess disease risk up to 15 years before symptoms start. By analyzing blood samples from over 50,000 people, the team found proteins that began changing in expression up to a decade before clinical onset of dementia. Their AI algorithm, combined with demographic information, shows promise in accurately predicting future dementia, offering potential cost benefits compared to current screening methods. The study, while limited in diversity and scope, provides clues for new treatments and intervention strategies, with ongoing research on other brain-related conditions.
Originally Published 1 year ago — by Nature.com
A study analyzing blood proteins has identified biomarkers that can predict the risk of developing dementia up to 15 years before diagnosis, potentially leading to the development of blood tests for early detection of diseases such as Alzheimer's. High levels of four proteins - GFAP, NEFL, GDF15, and LTBP2 - were found to be strongly associated with dementia, and a predictive model combining these biomarkers with demographic factors showed about 90% accuracy in predicting the incidence of dementia subtypes more than ten years before diagnosis. While the findings are promising, further validation is needed before these biomarkers can be used as clinical screening tools.
Originally Published 2 years ago — by Neuroscience News
A study analyzing blood serum from 113 patients has revealed significant findings in the fight against Long Covid, indicating dysregulated activation of the complement system, altered coagulation, and ongoing thromboinflammatory responses. These findings offer potential biomarkers for diagnosing Long Covid and open new avenues for developing effective treatments. About 20% of COVID-19 patients and 5% of all infected individuals develop Long Covid, which lacks effective treatment, making these discoveries crucial for future diagnostic and therapeutic research.
Originally Published 2 years ago — by Nature.com
Researchers have identified potential blood protein biomarkers for diagnosing and monitoring long COVID, a condition affecting an estimated 65 million people worldwide. A computational model based on the analysis of over 6,500 proteins in blood samples from COVID-19 patients suggests that immune response, blood clotting, and inflammation may play key roles in long COVID. The study's findings could pave the way for further research and potential therapies, although larger studies are needed to fully understand the underlying causes of the condition.
Originally Published 2 years ago — by NBC News
A new study has identified persistent changes in blood proteins in people with long Covid, indicating that their immune system remains on high alert for months after the acute infection, potentially explaining the debilitating symptoms. The findings could pave the way for diagnostic tests and treatments, focusing on the complement system proteins. However, further research and replication of the results are needed, and future studies should follow patients for longer periods to better understand the long-term effects of long Covid.
Originally Published 2 years ago — by Hindustan Times
US researchers have developed a new DNA test that can analyze proteins in the blood to detect 18 different types of early-stage cancers across major human organs with high accuracy. This multi-screening test has the potential to reshape cancer screening guidelines and become a standard part of routine check-ups, potentially leading to improved treatment and higher survival rates. The test, developed by the US biotech firm Novelna, outperforms previous methods and could help diagnose pre-cancerous and early-stage cancer before significant damage occurs, although further studies are needed to establish its effectiveness.
Originally Published 2 years ago — by The Guardian
Scientists have developed a DNA test that can detect 18 early-stage cancers by analyzing proteins in the blood, potentially revolutionizing cancer detection. The test outperformed existing methods and showed high accuracy in identifying cancer types and their origins. While the findings are promising, further studies are needed to confirm the test's effectiveness on a larger scale. If successful, this test could significantly improve early cancer detection and reshape screening guidelines.
Originally Published 2 years ago — by Endpoints News
The Pharma Proteomics Project, a collaboration between 13 pharmaceutical companies and the UK Biobank, has discovered numerous new leads for drug targets and diagnostic biomarkers by analyzing genetic data and blood proteins from 54,000 individuals. This research has the potential to uncover the causes of common conditions and has revealed thousands of previously unknown associations between common genetic variants and circulating proteins in the blood.