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Universal Flu Vaccine

All articles tagged with #universal flu vaccine

Toward a world without flu: universal vaccines gain ground
future-perfect5 days ago

Toward a world without flu: universal vaccines gain ground

The current flu season is unusually harsh with high illness and hospitalization numbers and low vaccination rates, but researchers are pursuing a set of universal flu vaccine approaches (targeting the HA stem, mosaic nanoparticle displays, and neuraminidase/T-cell–based strategies) plus longer-lasting preventives. If these efforts succeed and are paired with faster vaccine updates, the world could see dramatically reduced infections and severe illnesses in future winters, though funding and public acceptance remain challenges.

"CDC Activated After Bird Flu Alert as South Dakota Cattle Herd Tests Positive"
health-science1 year ago

"CDC Activated After Bird Flu Alert as South Dakota Cattle Herd Tests Positive"

Bill Gates had previously warned about the risk of pandemics and called for the development of a universal flu vaccine. The CDC has been "activated" after issuing a bird flu alert following a Texas man's infection from close contact with an infected cow. Scientists are concerned about the potential of a pandemic worse than COVID if the bird flu mutates. The CDC is prepared for what may be ahead, while investors are eyeing mRNA vaccine-makers' stocks in light of escalating fears around the bird flu virus.

"Duke Researchers Innovate Long-Lasting Flu Vaccine"
health2 years ago

"Duke Researchers Innovate Long-Lasting Flu Vaccine"

Researchers at Duke University are working on developing a universal flu vaccine that could provide longer-lasting protection against multiple flu strains. The vaccine aims to target all types of influenza, not just the anticipated dominant strain of the season. Recent discoveries of antibodies that target various flu strains have shown promising results in mice, and the team plans to test the vaccine in primates in the next two years. If successful, human trials could follow, potentially offering a more effective and longer-lasting alternative to the current annual flu shot.

Advancements in Universal Flu Vaccine Trials Amid Rising COVID and Flu Cases
health2 years ago

Advancements in Universal Flu Vaccine Trials Amid Rising COVID and Flu Cases

As cases of respiratory illnesses, including flu, RSV, and COVID-19, continue to rise in several states, the Centers for Disease Control and Prevention (CDC) is recommending an RSV vaccine for adults over 60 and pregnant women. Meanwhile, the Cleveland Clinic is preparing for human trials of a universal flu vaccine that would protect against all strains of the virus, with trials expected to begin in 2024 and 2025. The CDC is also monitoring a rising COVID subvariant called JN.1, which currently accounts for over 20% of cases nationwide, but there is no evidence suggesting it is more severe or that existing tests, vaccines, and treatments would be ineffective.

"Universal Flu Vaccine Human Trials Imminent as COVID and Flu Cases Surge"
health2 years ago

"Universal Flu Vaccine Human Trials Imminent as COVID and Flu Cases Surge"

As respiratory illness cases, including flu and RSV, rise in several states, the Centers for Disease Control and Prevention (CDC) is recommending an RSV vaccine for adults over 60 and pregnant women. Meanwhile, the Cleveland Clinic is preparing for human trials of a universal flu vaccine that would protect against all strains of the virus, with trials expected to begin in 2024 and 2025. The CDC is also monitoring a rising COVID subvariant called JN.1, which currently accounts for over 20% of cases nationwide, but there is no evidence suggesting it is more severe or that existing tests, vaccines, and treatments would be ineffective.

"Universal Flu Vaccine Human Trials Imminent as COVID and Flu Cases Surge"
health2 years ago

"Universal Flu Vaccine Human Trials Imminent as COVID and Flu Cases Surge"

As respiratory illness cases, including flu and RSV, rise in several states, the Centers for Disease Control and Prevention (CDC) is recommending an RSV vaccine for adults over 60 and pregnant women. Meanwhile, the Cleveland Clinic is preparing for human trials of a universal flu vaccine that would protect against all strains of the virus, with trials expected to begin in 2024 and 2025. The CDC is also monitoring a rising COVID subvariant called JN.1, which currently accounts for over 20% of cases nationwide, but there is no evidence suggesting it is more severe or that existing tests, vaccines, and treatments would be ineffective.

"NIH Launches Human Trials for Promising Universal Flu Vaccine"
health2 years ago

"NIH Launches Human Trials for Promising Universal Flu Vaccine"

The National Institutes of Health (NIH) has initiated a Phase 1 clinical trial for a new universal influenza vaccine candidate, FluMos-v2, which targets six strains of the flu. The trial aims to evaluate the vaccine's safety and its ability to elicit an immune response. Currently available flu vaccines are designed to protect against specific strains, but a universal vaccine could provide broader protection against multiple strains. The investigational vaccine, developed by researchers at NIH's Vaccine Research Center, displays part of the influenza virus protein on self-assembling nanoparticle scaffolds to stimulate the immune system. The trial will enroll 24 healthy volunteers, who will receive two injections of the vaccine candidate.

"Universal flu vaccine trials show promise for long-term protection"
health2 years ago

"Universal flu vaccine trials show promise for long-term protection"

The National Institutes of Health has started enrolling volunteers for a clinical trial of a universal flu vaccine that uses the same mRNA technology as the COVID-19 vaccines from Pfizer and Moderna. The new vaccine focuses on a portion of the flu virus that is common across all strains of flu, making it “universal” and greatly improves the manufacturing speed by utilizing the mRNA platform. If successful, it could mean a significantly more effective flu vaccine year to year, and potentially change the way we vaccinate against flu.

NIH begins human trial for mRNA-based universal flu vaccine.
health2 years ago

NIH begins human trial for mRNA-based universal flu vaccine.

The National Institutes of Health is enrolling 50 volunteers for a Phase 1 clinical trial at Duke University to test an experimental universal influenza vaccine using mRNA technology. The trial will evaluate the best dosage for the vaccine while comparing its safety and efficacy to current seasonal flu vaccines. A universal flu vaccine could eliminate the need for annual development of seasonal influenza vaccines and serve as an important line of defense against the spread of a future flu pandemic.

NIH to test mRNA-based universal flu vaccine.
health2 years ago

NIH to test mRNA-based universal flu vaccine.

The National Institutes of Health has started enrolling patients in an early-stage clinical trial to test a universal flu vaccine based on messenger RNA technology. The vaccine is expected to protect against a wide variety of flu strains and provide long-term immunity. The trial will enroll up to 50 healthy people to test whether the experimental shot is safe and produces an immune response. The current generation of flu vaccines provides important protection against hospitalization, but the effectiveness of the shots can vary widely from year to year.