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Rem Sleep Behavior Disorder

All articles tagged with #rem sleep behavior disorder

science3 days ago•14 min saved

Parkinson's Early Clues: Smell Loss, Sleep Behaviors, and the Quest for Prevention

Parkinson's disease is discussed as a neurodegenerative condition linked to misfolded alpha-synuclein, with early non-motor signs such as reduced sense of smell and REM sleep behavior disorder often appearing years before tremors; evidence suggests initiation in the nose or gut with brain-wide spread, while environmental factors like air pollution, pesticides, and solvents may raise risk and drive prevention efforts. The Parkinson's Progression Markers Initiative aims to detect the disease earlier with biomarkers (e.g., alpha-synuclein assays) to speed treatments, but no current therapy slows progression; emphasis on exercise and sleep as important, potentially protective, interventions.

via Science Friday|

#alpha-synuclein #early-signs #environmental-risk-factors

health1 year ago•5 min saved

"Link Between Acting Out Dreams and Parkinson’s Disease"

Acting out dreams, known as dream enactment, can indicate underlying health issues such as Parkinson's disease, obstructive sleep apnea, and PTSD. Approximately 1% of people over 50 experience REM sleep behavior disorder (RBD), where the body loses paralysis during dreaming, leading to potential injury. RBD is strongly linked to a high risk of developing Parkinson's disease, with 80% of RBD patients developing Parkinson's 15 to 20 years later. Researchers are studying RBD to understand early Parkinson's progression and develop preventive therapies, while patients are encouraged to seek medical evaluation and participate in research initiatives for early diagnosis and planning.

via The Washington Post|

#dream-enactment #health #neuroscience

health2 years ago•7 min saved

Sleep Disorder Linked to Parkinson's Disease: Acting Out Dreams as a Warning Sign

Researchers are studying REM sleep behavior disorder (RBD), a condition where individuals physically act out their dreams, and its strong link to neurodegenerative diseases like Parkinson's. The NAPS Consortium aims to collect extensive data on RBD to lay the foundation for future clinical trials of neuroprotective treatments. Bioelectronic devices and treatments like transcranial magnetic stimulation are being explored as potential therapies. RBD can be an early sign of neurodegenerative diseases, and researchers hope to develop interventions to delay or prevent their development.

via Neuroscience News|

#health #naps-consortium #neurodegenerative-diseases

health2 years ago•4 min saved

The Link Between a Sleep Disorder and Dementia/Parkinson's Disease

REM sleep behavior disorder, a little-known sleep disorder that causes people to act out their dreams, has been linked to neurodegenerative brain diseases such as Parkinson's disease and dementia with Lewy bodies. The disorder affects around 1% of the general population worldwide and about 2% of adults over 65. REM sleep behavior disorder may be the first symptom of these diseases and can occur at any time during the disease process. Early diagnosis provides an opportunity to study how the disease progresses in the brain and to develop therapies that could either slow this process or prevent it from happening.

via Scroll.in|

#dementia #health #neurodegenerative-disorders

health2 years ago•4 min saved

The Link Between a Little-Known Sleep Disorder and Dementia

REM sleep behavior disorder, a little-known sleep disorder that affects around 1% of the general population, can foreshadow neurodegenerative brain diseases such as Parkinson's disease and dementia with Lewy bodies. The disorder causes patients to act out their dreams, often violently, resulting in injuries. It may be caused by something specific, such as obstructive sleep apnea, narcolepsy, psychiatric disorders, use of antidepressants, autoimmune disorders, and brain lesions. REM sleep behavior disorder may be the first symptom of Parkinson's disease or dementia with Lewy bodies, and an early diagnosis can help study how the disease progresses in the brain and develop therapies that could either slow this process or prevent it from happening.

via ScienceAlert|

#dementia #health #neurodegenerative-disorders

health2 years ago•4 min saved

Little-known sleep disorder linked to dementia and Parkinson's.

REM sleep behavior disorder (RBD) is a little-known sleep disorder that occurs during the rapid eye movement (REM) stage of sleep and affects around 1% of the general population worldwide. RBD has been linked to neurodegenerative brain diseases such as Parkinson’s disease and dementia with Lewy bodies. RBD may be the first symptom of these diseases and can occur at any time during the disease process. An early diagnosis of RBD can provide an opportunity to study how the disease progresses in the brain and to develop therapies that could either slow this process or prevent it from happening.

via OregonLive|

#dementia #health #neurodegenerative-disorders

health2 years ago•4 min saved

Unraveling the Link Between Sleep Disorder and Dementia: Expert Answers 4 Key Questions

REM sleep behavior disorder (RBD) is a little-known sleep disorder that affects around 1% of the general population worldwide and about 2% of adults over 65. It is characterized by acting out dreams during the rapid eye movement (REM) stage of sleep, often resulting in injuries. RBD has clear links to neurodegenerative brain diseases such as Parkinson’s disease and dementia with Lewy bodies, and may be the first symptom of these diseases. Early diagnosis of RBD provides an opportunity to study how the disease progresses in the brain and to develop therapies that could either slow this process or prevent it from happening.

via Yahoo News|

#dementia #health #neurodegenerative-disorders

health2 years ago•4 min saved

Unraveling the Link Between Sleep Disorder and Dementia: Expert Answers 4 Key Questions

REM sleep behavior disorder (RBD) is a little-known sleep disorder that affects around 1% of the general population worldwide and about 2% of adults over 65. It is characterized by acting out dreams during the rapid eye movement (REM) stage of sleep, often resulting in injuries. RBD has clear links to neurodegenerative brain diseases such as Parkinson’s disease and dementia with Lewy bodies. Early diagnosis of RBD can provide an opportunity to study how the disease progresses in the brain and to develop therapies that could either slow this process or prevent it from happening.

via The Conversation Indonesia|

#dementia #health #neurodegenerative-disorders

health2 years ago•4 min saved

Revolutionary Therapy for Violent Dreaming in REM Sleep Disorder.

Researchers at Mount Sinai Hospital have identified a new potential treatment for rapid eye movement (REM) sleep behavior disorder, a condition that affects over 3 million Americans and involves acting out dreams during sleep. The study established a new model detailing the disorder’s progression due to neurodegeneration linked with tau protein accumulation. Dual orexin receptor antagonists, used commonly for insomnia, were found to significantly reduce symptoms of this disorder, opening up a promising new treatment option that could potentially have fewer side effects.

via Neuroscience News|

#dual-orexin-receptor-antagonists #health #neurodegeneration

health2 years ago•4 min saved

Gut bacteria linked to Parkinson's disease.

Researchers at The Chinese University of Hong Kong have found that the gut microbiome holds Parkinson's disease markers and may indicate a method of early diagnosis. The study found gut microbiota compositions significantly altered in early PD and REM sleep behavior disorder (RBD) compared with controls and the relative cohort. The observations open the door for future research to go beyond the correlations and seek the early causative path of both diseases in hopes of discovering what could be a pre-clinical diagnostic intervention to prevent Parkinson's from developing in the first place.

via Medical Xpress|

#alpha-synucleinopathy #early-diagnosis #gut-microbiome

health2 years ago•4 min saved

The Gut-Brain Connection in Neurodegenerative Diseases: Insights and Discoveries.

Changes in gut microbiota occur in the earliest stages of Parkinson's disease, and a new study shows these can start before the onset of symptoms. Researchers from China and Germany looked at the bacteria in the guts of people with early Parkinson's disease, people with REM sleep behavior disorder (RBD), their close relatives, and healthy people. Similar bacterial changes were observed in the guts of people with RBD and those with Parkinson's disease, with some beneficial bacteria being depleted and some harmful bacteria becoming more abundant. The study has limitations, but it's important research as early diagnosis is a major challenge in the fight against Parkinson's disease.

via ScienceAlert|

#biomarkers #early-diagnosis #gut-microbiota