All articles tagged with #psychosis
The HBO Max drama The Pitt follows a law student who spirals into psychosis, highlighting how early, subtle signs emerge over months and how his family's response and the show's portrayal contribute to broader conversations about mental health.
A large U.S. study of 463,396 adolescents aged 13–17 found that past-year cannabis use is associated with about twice the risk of developing psychotic and bipolar disorders by age 26, and higher risks of depression and anxiety, based on universal pediatric screening and electronic health records from 2016–2023. With cannabis potency rising, public health experts call for reducing potency and limiting youth marketing, and stress the need for accurate, evidence-based information for families.
Bristol Myers Squibb bets that Cobenfy, a 30-year-old drug, can become the first approved treatment for psychosis in Alzheimer's disease; its fate hinges on three pivotal trials later this year after a long-ago trial showed promise but was marred by adverse effects, a rescue journey from Eli Lilly to Karuna Therapeutics before landing with BMS.
A CMAJ analysis of Ontario birth cohorts finds psychotic-disorder diagnoses rose 60% among ages 14–20 between 1997 and 2023, and those born in the early 2000s are roughly twice as likely to be diagnosed by age 20; researchers suggest rising cannabis and other substance use among teens may be contributing and urge more study.
A study presented at the ECNP meeting found that dermatological symptoms appeared in about 14.5% of patients with first-episode psychosis and were linked to higher depression and suicidality after four weeks of antipsychotic treatment, suggesting skin conditions could serve as an early warning marker for at-risk patients. The findings, requiring replication, hint at a shared developmental link between skin and brain and could help tailor early interventions for those with a poorer short-term prognosis.
AI does not yet cause psychosis, but interactive genAI can reinforce delusional beliefs in people with vulnerable reality-testing, making clinical guidance and safeguards essential. Clinicians urge research, ethical considerations, and collaboration with AI developers to prevent harm as AI becomes more integrated into daily life.
Scientists have discovered that mutations in the GRIN2A gene can cause serious mental illnesses like schizophrenia and depression, often starting in childhood. This breakthrough suggests that genetic testing could identify individuals at risk and that targeted treatments, such as L-serine supplements, may help manage or even cure these conditions, offering hope for personalized mental health care.
A study analyzing real-world data suggests that the new schizophrenia drug Cobenfy is most effective for patients with negative symptoms like social withdrawal, supporting the move toward precision psychiatry by identifying biological subtypes of psychosis that respond differently to treatment.
Research indicates that patients experiencing their first episode of psychosis with skin conditions are at a higher risk of depression and suicidality, suggesting skin issues could serve as early markers for severe psychiatric outcomes due to shared developmental and inflammatory pathways between the brain and skin.
A study in JAMA Psychiatry links marijuana legalization to a nearly 10% increase in use among people with psychosis, raising concerns about public health and safety. Despite evidence of health risks, including the potential to cause psychosis, pro-legalization efforts continue, though public support is waning as awareness of harms grows. Experts call for stronger regulation and honest messaging to address these issues.
The author recounts her mother's 15-year life living off-grid with her husband Mark in a remote mountain cabin, exploring themes of resilience, dependency, and mental health, culminating in her mother's diagnosis of folie à deux and her subsequent health decline, highlighting the complex dynamics of their relationship and the impact of isolation and caregiving.
The article explores how different cultures perceive and treat hearing voices, with some viewing it as a spiritual or positive experience, contrasting with Western psychiatry's view of it as a symptom of psychosis, highlighting cultural influences on mental health perceptions and outcomes.
The article discusses schizophrenia, a complex and often misunderstood mental illness affecting millions worldwide, highlighting its symptoms, causes, societal stigma, and the importance of treatment, with a focus on personal stories like Henry Cockburn's journey to manage the disorder.
A systematic review links high-potency THC cannabis to increased risks of mental health issues such as psychosis, schizophrenia, and cannabis use disorder, but emphasizes the need for more rigorous research to provide clear guidance.
A systematic review of 99 studies found that high-THC cannabis products are linked to increased risks of psychosis, schizophrenia, and cannabis use disorder, with some inconsistent evidence suggesting potential benefits for anxiety and depression. The research emphasizes the need for better-designed studies to clarify these effects.