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Neural Stem Cells

All articles tagged with #neural stem cells

health1 year ago

Nasal Spray Shows Promise in Alzheimer's Treatment

Researchers at Texas A&M University have developed a potential treatment for Alzheimer's disease using a nasal spray containing extracellular vesicles derived from human neural stem cells. This non-invasive method targets chronic neuroinflammation, reducing amyloid-beta plaques and Tau accumulation, and improving cognition and mood in animal models. The treatment alters microglia gene expression, reducing harmful inflammation while maintaining their ability to clear amyloid-beta. The approach could delay Alzheimer's progression by 10 to 15 years, with further studies planned to confirm its efficacy.

neuroscience2 years ago

Unveiling Lactate's Crucial Role in Neural Stem Cell Development

Researchers at Tohoku University have discovered that lactate, a byproduct of exercise and metabolism, plays a critical role in the development of neural stem cells into specialized neurons. Lactate sends signals to these cells, modifying and strengthening neuronal functions. The findings suggest that lactate signaling could be harnessed to prevent or control cognitive diseases. This study provides new insights into the mechanisms by which lactate affects brain development and neuronal differentiation, potentially paving the way for future therapeutic interventions.