Scientists are developing a potential exercise-mimicking pill called SLU-PP-332, which has shown promising results in rodent cells by increasing fatigue-resistant muscle fibers and improving endurance. The compound, designed to mimic the activation of estrogen-related receptors, could potentially benefit those unable to exercise due to illness or disability, or aid in muscle recovery after rapid weight loss. While human trials are still years away, the prospect of a safe pill that mimics exercise is generating excitement in the field of future medicine.
Brain-computer interfaces (BCIs) are advancing, with devices like the Stentrode offering wireless, minimally invasive options for patients with severe disabilities. Neurosurgeon Shahram Majidi discusses the intricate surgical process and the life-changing impact on patients, envisioning a future where BCIs become routine procedures for various conditions. As the field progresses, he anticipates a growing demand for BCI surgeons and the potential for expanding BCI applications beyond paralysis to treat conditions like seizures, depression, and eating disorders.
Nasal sprays are not just for allergies anymore. They are already being used to treat migraines, depression, opioid overdose, and deliver flu vaccines. In the future, nasal sprays could be used for treating rapid heartbeats, COVID, severe allergic reactions, and delivering vaccines. Nasal sprays have advantages such as easy application and faster absorption into the bloodstream. However, there are challenges like nosebleeds and difficulty penetrating thick mucus. While nasal sprays show potential for antiviral use, more research is needed before they become a reliable option for vaccines.
The FDA has approved Roctavian, a gene therapy treatment for severe hemophilia A, a rare and potentially fatal blood disorder. The treatment involves a single infusion that inserts missing genes and could eliminate the need for frequent injections. Roctavian is the latest in a series of FDA-approved gene therapies, signaling the potential for gene therapy to revolutionize the treatment of various diseases. However, the high cost of gene therapies remains a significant barrier to widespread use.
