Tag

Epigenetic Reprogramming

All articles tagged with #epigenetic reprogramming

"Unlocking the Potential: Epigenetic Reprogramming and Aging Reversal"

Originally Published 1 year ago — by Longevity.Technology

Featured image for "Unlocking the Potential: Epigenetic Reprogramming and Aging Reversal"
Source: Longevity.Technology

A recent review proposes the Information Theory of Aging (ITOA) to explore whether epigenetic reprogramming can restore youthful epigenetic information and reverse aging. The theory suggests that disturbances in the epigenome play a crucial role in aging and that epigenetic noise can accelerate the process. Studies have shown that aging is not only driven epigenetically but also reversible, and the review discusses the potential of epigenetic reprogramming to reverse age-related information loss. The ITOA makes predictions that in vivo epigenetic reprogramming might be able to reverse aging hallmarks, but further studies are needed to develop more accurate approaches to rejuvenate the epigenome and restore youthful tissue functions.

"ARVO 2023: Life Biosciences and Iveric Bio showcase promising vision restoration data in nonhuman primates and clinical trials"

Originally Published 2 years ago — by GlobeNewswire

Featured image for "ARVO 2023: Life Biosciences and Iveric Bio showcase promising vision restoration data in nonhuman primates and clinical trials"
Source: GlobeNewswire

Life Biosciences presented preclinical data at the Association for Research in Vision and Ophthalmology (ARVO) conference demonstrating the ability to restore visual function in nonhuman primates (NHP) after delivery of a novel gene therapy candidate using a partial epigenetic reprogramming approach. The therapy significantly restored visual function in an NHP model of non-arteritic anterior ischemic optic neuropathy (NAION), a disorder similar to a stroke of the eye that is characterized by painless yet sudden loss of vision. The approach partially reprograms cells to resemble a more youthful state while retaining their original cellular identity.