"ARVO 2023: Life Biosciences and Iveric Bio showcase promising vision restoration data in nonhuman primates and clinical trials"
Life Biosciences presented preclinical data at the Association for Research in Vision and Ophthalmology (ARVO) conference demonstrating the ability to restore visual function in nonhuman primates (NHP) after delivery of a novel gene therapy candidate using a partial epigenetic reprogramming approach. The therapy significantly restored visual function in an NHP model of non-arteritic anterior ischemic optic neuropathy (NAION), a disorder similar to a stroke of the eye that is characterized by painless yet sudden loss of vision. The approach partially reprograms cells to resemble a more youthful state while retaining their original cellular identity.