All articles tagged with #dark genome
Research suggests that tiny genetic differences in the 'dark' regions of our DNA, specifically in an enhancer region called EC 1.45, may explain why Neanderthals had distinct facial features like larger jaws and noses compared to modern humans, with these differences linked to variations in gene regulation during development.
Researchers are using artificial intelligence to explore the "dark genome," the portion of the genome that does not code for proteins, in order to better understand how cancer grows. By analyzing this non-coding DNA, scientists hope to uncover new insights into the mechanisms behind cancer development and potentially identify new targets for treatment.
Researchers have made a breakthrough in understanding LINE-1, an ancient genetic element found in the "dark genome" that is associated with various diseases. The study provides high-resolution images and structural details of LINE-1 and its reverse transcriptase enzyme, revealing similarities to HIV-1 reverse transcriptase. This discovery opens up potential pathways for targeted drug development and treatment of diseases such as cancer, autoimmune disorders, neurodegeneration, and aging.
Researchers have provided the first high-resolution images and structural details of LINE-1, an ancient genetic element that inserts itself into the human genome and is implicated in diseases such as cancer, autoimmune disorders, neurodegeneration, and aging. This study sheds light on a small part of the "dark genome" and offers a foundation for potential treatments targeting LINE-1 related diseases.
A multidisciplinary study published in Nature has revealed the structure of LINE-1, an ancient genetic parasite that makes up a significant portion of our DNA. LINE-1, also known as a "jumping gene," has the potential to cause mutations and is associated with autoimmune diseases, cancer, and neurodegeneration. Understanding the structure and function of LINE-1 could lead to the development of new treatments for these conditions and provide insights into the mysteries of the "dark genome."
The human genome contains 20,000 protein-coding genes, but they account for just 2% of our DNA. The remaining 98% of our DNA became known as dark matter, or the dark genome, a mysterious melee of letters with no obvious meaning or purpose. Now, two decades on, we have the first inklings of the role of the dark genome. Its primary function appears to be regulating the decoding process, or expression, of protein-making genes. It helps to control how our genes behave in response to all the environmental pressures our bodies face throughout our lives, ranging from diet to stress, pollution, exercise, and how much we sleep, a field known as epigenetics.