Unraveling the Dark Genome: Ancient Genetic Parasite Holds Disease Treatment Key
Researchers have made a breakthrough in understanding LINE-1, an ancient genetic element found in the "dark genome" that is associated with various diseases. The study provides high-resolution images and structural details of LINE-1 and its reverse transcriptase enzyme, revealing similarities to HIV-1 reverse transcriptase. This discovery opens up potential pathways for targeted drug development and treatment of diseases such as cancer, autoimmune disorders, neurodegeneration, and aging.
