A doctor shares his personal experience and discusses the complexities of stopping antidepressants, particularly SSRIs, highlighting the need for personalized tapering methods and better understanding of withdrawal symptoms to improve mental health treatment.
Bella Mackie shares her personal experience with long-term use of antidepressants, the challenges of tapering off SSRIs, and the lack of adequate information and support from healthcare providers about withdrawal symptoms, highlighting the need for better guidance and awareness.
A study finds that longer use of antidepressants is linked to more severe, longer-lasting withdrawal symptoms, especially after more than two years of use, highlighting the need for careful discontinuation strategies and updated clinical guidelines.
Outro Health, a US telehealth startup launched in seven states, offers a guided, hyperbolic tapering program to help people safely discontinue antidepressants, addressing the challenges of withdrawal and the growing demand for mental health support. The service pairs patients with clinicians and uses custom compounded drugs to facilitate gradual dose reduction, aiming to improve the withdrawal experience and promote informed de-prescribing.
Gretchen Walsh led the Virginia Cavaliers to an NCAA title in the 200 medley relay with a record-breaking 50 back swim, emphasizing that their consistent tapering approach between ACC and NCAA Championships has been successful for her. She explained that they incorporate a week of hard work after ACCs before tapering down for NCAAs, highlighting their dedication to not taking the easy way out.
A doctor who has been taking semaglutide drug Ozempic for a year to lose weight is trying a "maintenance dose" approach to avoid regaining weight after stopping the medication. He believes that tapering off the medication slowly could help the body adjust to its new size and metabolism. While there are no established best practices for coming off Ozempic, doctors suggest tapering and adding other weight-management medications to avoid rapid rebound issues with GLP-1s.
Antidepressant withdrawal symptoms can last for weeks, months, or even years, and are often misinterpreted as a relapse in depression. Guidelines now recommend tapering off antidepressants over months and sometimes years down to very low doses. The approach to tapering recommended by these updated guidelines is called “hyperbolic tapering”. It is based on the fact that very small doses of antidepressants have very large effects on the brain. This technique can help people who were previously not able to stop their medication with traditional approaches to safely stop it.