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Nonalcoholic Fatty Liver Disease

All articles tagged with #nonalcoholic fatty liver disease

health2 years ago

17 Genetic Loci Linked to Nonalcoholic Fatty Liver Disease Identified in Meta-Analysis

A genome-wide association meta-analysis has identified 17 genetic loci associated with nonalcoholic fatty liver disease (NAFLD). The study analyzed data from over 1.1 million individuals of diverse ancestries and found genetic variants that influence the risk of NAFLD, providing insights into the underlying biology of the disease. The findings highlight the importance of genetic factors in the development of NAFLD and may lead to improved understanding, prevention, and treatment of this common liver disorder. Data from the study is publicly available for further research.

via Nature.com|
#data-availability#genetic-variants#genome-wide-association-study
health2 years ago

Lilly's 'Triple-G' Obesity Drug Shows Strong Results in Alleviating Fatty Liver Disease.

Eli Lilly's experimental obesity drug, retatrutide, significantly reduced liver fat in a small clinical trial of 98 patients with nonalcoholic fatty liver disease. Patients on the highest dose experienced an 86% decrease in liver fat over 48 weeks, with 93% achieving resolution of the disease. The results support further studies of the treatment against the increasingly common condition that lacks approved treatments.

via STAT|
#clinical-trial#eli-lilly#health
healthcare2 years ago

ADA recommends screening for nonalcoholic fatty liver disease in all diabetes patients.

The American Diabetes Association recommends that all adults with type 2 diabetes or prediabetes should be screened for nonalcoholic fatty liver disease, which can lead to serious liver damage. GLP-1 treatments, such as Ozempic and Mounjaro, are singled out as an option doctors could consider, as they have been shown to lower blood sugar and cut weight. However, there are no approved medications for the disease, and there is still limited data on the efficacy of GLP-1s in fatty liver disease.

via STAT|
#american-diabetes-association#diabetes-drugs#glp-1-treatments
health2 years ago

The Alarming Rise of Fatty Liver Disease in the US

Rates of nonalcoholic fatty liver disease (NAFLD) have been increasing rapidly over the past three decades, with more than a third of adult participants in a recent study developing the condition. Hispanic Americans, especially Mexican Americans, are disproportionately affected by the disease, which is caused by fat building up to abnormal levels in the liver. Certain genes and metabolic disorders, such as obesity, diabetes, pre-diabetes, high blood pressure, and high cholesterol, are known to raise the risk of NAFLD, a leading cause of liver transplantation. Weight loss can make a big difference, but being thin may not completely protect against NAFLD.

via Yahoo News|
#diabetes#health#metabolic-disorders
health2 years ago

Fatty Liver Disease on the Rise in America

Rates of nonalcoholic fatty liver disease (NAFLD) have been increasing rapidly over the past three decades, with more than a third of adult participants in a recent study developing the condition. Hispanic Americans, especially Mexican Americans, are disproportionately affected by the disease, which is linked to obesity, diabetes, pre-diabetes, high blood pressure, and high cholesterol. Although there is no medication approved to treat NAFLD, it can be reversed through lifestyle modifications such as exercise and weight loss. Experts suggest avoiding junk food and overly processed foods and cutting back on carbs to prevent the disease.

via NBC News|
#diabetes#health#metabolic-disorders
health2 years ago

Comparing Time-Restricted Eating and Calorie Restriction for NAFLD and Intermittent Fasting's Potential Benefits.

A recent study published in JAMA Network Open found that time-restricted eating did not provide additional benefits in reducing intrahepatic triglyceride content in obese patients with nonalcoholic fatty liver disease compared to daily calorie restriction. Both groups showed similar reductions in triglyceride content, body weight, and metabolic risk factors. The study suggests that time restriction alone is no more effective than calorie restriction in reducing body fat and visceral fat among individuals with obesity.

via Medical Xpress|
#calorie-restriction#health#nonalcoholic-fatty-liver-disease