Researchers have identified a unique brain network associated with schizophrenia by analyzing data from over 90 studies involving more than 8,000 participants. This network, which connects areas of brain atrophy like the insula and hippocampus, is consistent across different stages and symptoms of schizophrenia and distinct from other psychiatric conditions. The findings could lead to personalized treatments and clinical trials using transcranial magnetic stimulation to target this network.
A study in Nature Mental Health reveals that structural differences in the brain may affect how well adults with ADHD respond to stimulant medications like methylphenidate. Using MRI scans, researchers found that non-responders had smaller cortical volumes and surface areas in several brain regions compared to responders. The findings suggest that neuroanatomy plays a crucial role in treatment effectiveness, although the study's small sample size and focus on males limit its generalizability. Further research is needed to confirm these results and explore potential sex differences.
