"COVID-19 and Vaccines: New Findings and Insights"
Originally Published 2 years ago — by News-Medical.Net
A recent study posted to the bioRxiv preprint server suggests that transposable elements (TEs) play a crucial role in the host's response to COVID-19 and the development of illness. The study findings showed the differential expression and activation of distinct mobile genetic elements in response to SARS-CoV-2 infection. Specifically, the team identified and validated the infection-induced upregulation of the LTR69 subfamily of endogenous retroviruses. LTR69-Dup69 was also found to possess enhancer activity and exhibit sensitivity to the transcription factors IRF3 and p65/RelA.