Tag

Heritability

All articles tagged with #heritability

science20 days ago•6 min saved

When External Deaths Decline, Genes Take a Bigger Share of Lifespan

A twin-based study shows that removing deaths from accidents and infections raises the estimated genetic contribution to lifespan from about 20–25% to roughly 50–55%. This higher heritability reflects context and population, not stronger genes: as external threats decline, environmental and lifestyle factors still shape outcomes, and half of lifespan variation remains due to environment. The finding emphasizes that genes and environment interact, and aging genetics requires considering different contexts.

via ScienceAlert|

#aging #environment #genetics

health28 days ago•57 min saved

Lifespan may be half-genetic, new study suggests

A new analysis published in Science estimates that intrinsic lifespan is about 50% heritable after accounting for extrinsic death causes like accidents and infections, using twin data from Sweden, Denmark, and the U.S. This method contrasts with older estimates (6–25%) and suggests genetics play a larger role than previously thought, though environment and lifestyle remain crucial. The research was limited mainly to Northern European populations, and further work is needed to confirm applicability across diverse groups and to translate findings into aging interventions aimed at extending healthspan.

via Live Science|

#aging #genetics #health

science1 month ago•3 min saved

Genes Drive About Half of Human Lifespan, New Study Finds

A study in Science argues that genetics accounts for roughly 50% of variation in human lifespan after removing the masking effect of extrinsic mortality (accidents, disease, etc.), suggesting genes governing ageing are substantial contributors. Using a math model and twin data from Denmark and Sweden, the researchers found heritability around 50% and noted that as environmental risks declined over the 20th century, genetic influence becomes more evident. The work implies future therapies could target ageing mechanisms, though lifestyle and environment still play a major role, varying by cause of death and age.

via The Guardian|

#aging #extrinsic-mortality #genetics

health-and-science2 years ago•3 min saved

"Study Reveals Genetic Influence on ADHD"

A study of a large number of twins suggests that ADHD behaviors exhibit a notable degree of heritability, with 11% of the variation in children's ADHD behaviors attributed to shared genetic factors between generations. The study indicates that children tend to resemble their parents in levels of impulsiveness, hyperactivity, and inattention due to shared genetic influences rather than shared home environments or effects of parental ADHD on child ADHD. While genetic factors play a significant role, the main cause of ADHD is likely an interplay of unique environmental factors for each child.

via PsyPost|

#adhd #genetics #health-and-science

health2 years ago•3 min saved

Comparing Genetic Risk and Prevalence of Multiple Sclerosis in Different Populations

A Swedish study found that the risk of developing multiple sclerosis (MS) is similar between first- and second-degree family members of people with relapsing-remitting MS (RRMS) and primary progressive MS (PPMS). The study suggests that genetics and environment contribute equally to disease risk and that the likelihood of developing a particular MS type may be independent of genetics. The heritability of MS overall was estimated to be about 51%, with RRMS having a heritability of 55%. The study highlights the need for further research to explore other genetic and environmental risk factors that contribute to disease expression.

via Multiple Sclerosis News Today|

#genetic-risk #health #heritability