
Do Depression Supplements Really Work? Scientists Review 64 Products
A review of 209 clinical trials on 64 OTC products for depression found that some, like St John’s Wort, saffron, probiotics, and vitamin D, show promising results comparable to prescription antidepressants, while others have mixed or limited evidence. Few safety concerns were reported, but more rigorous research is needed to confirm effectiveness and safety, especially for popular but less-studied products.



