All articles tagged with #copd
Chuck Negron, founding lead singer of Three Dog Night behind hits like 'Joy to the World' and 'One,' died at 83 in Studio City from complications of heart failure and COPD; once plagued by drug issues, he sobered in 1991 and later reconciled with bandmates. He is survived by his wife Ami Albea Negron and five children, including Berry Oakley Jr.
Chuck Negron, founding member and lead vocalist of the LA rock band Three Dog Night, died at 83 in Studio City after battling COPD and heart failure. Born Charles Negron II in 1942 in the Bronx, he helped form Three Dog Night in 1967 with Danny Hutton and Cory Wells, delivering hits like Joy To The World and One. The group underwent lineup changes amid internal tensions and Negron’s struggles with addiction, though he later pursued a solo career and wrote an autobiography; he and Hutton reportedly reconciled last year. He is survived by his wife Ami Albea Negron and several children and relatives.
Chuck Negron, a founding member and lead vocalist of Three Dog Night, died at 83 in Los Angeles from complications of heart failure and COPD. He powered a string of late-1960s/early-70s hits including Joy to the World, One and An Old Fashioned Love Song, and also sang Easy To Be Hard and The Show Must Go On. Negron battled drug issues during the band’s rise, spent time in rehab, and found sobriety in 1991, later pursuing a solo career and writing Three Dog Nightmare. After years of estrangement, he reconciled with fellow member Danny Hutton last year. He is survived by wife Ami Albea Negron and five children, including Berry Oakley Jr.,
Chuck Negron, co-founder and lead singer of Three Dog Night, died at 83 at his Studio City home after decades-long COPD; he helped the band reach peak fame with hits like One and Joy to the World but battled heroin addiction that led to years on Skid Row and multiple rehab stints as the group split in 1976, reformed in 1982, and finally broke up again in 1985; Negron later pursued a solo career and published a memoir, Cory Wells died in 2015, and Danny Hutton still tours with Three Dog Night, with Negron and Hutton reportedly burying the hatchet last year.
Chuck Negron, co‑founder and lead singer of Three Dog Night and the voice behind hits like Joy to the World and One, died at 83 at his Studio City home. The band chalked up 21 Top 40 hits and gold albums, but Negron battled heroin addiction and COPD for decades, pursued rehab in 1991, and ultimately reconciled with former bandmates. His legacy endures in the trio’s classic catalog and his later solo work.
Feeling winded after climbing stairs can be a normal physiological response because stairs demand more oxygen and energy, but new or prolonged breathlessness warrants medical evaluation to rule out underlying conditions such as heart failure, obesity, COPD, or anemia. If recovery is quick, it’s usually not concerning; if breathing stays elevated for more than about three minutes or is accompanied by chest pain, headaches, or vision changes, consult a doctor. To improve stair endurance, gradually train and strengthen the muscles involved while addressing any medical issues first.
A new study highlights that COPD can affect people under 50, with 4.5% of adults in this age group diagnosed, and that early onset COPD is linked to higher risks of hospitalization and death. Smoking remains the primary risk factor, but non-smokers can also develop COPD. Early diagnosis and lifestyle changes, including quitting smoking and vaccination, are crucial for managing the disease and improving outcomes.
GSK and Hengrui Pharma have entered into agreements to develop up to 12 innovative medicines, including a potential best-in-class PDE3/4 inhibitor for COPD, with GSK paying $500 million upfront and the potential for up to $12 billion in milestone payments, aiming to expand their pipelines in respiratory, immunology, inflammation, and oncology.
Merck is acquiring Verona Pharma for approximately $10 billion to expand its portfolio with Ohtuvayre, a first-in-class COPD treatment approved by the FDA, aiming to enhance growth and innovation in respiratory therapies.
A recent study found that people with COPD have significantly more carbon particles in their lungs than smokers, with larger and more carbon-laden alveolar macrophages, indicating greater soot accumulation in COPD patients.
Sly Stone, the influential funk musician and leader of Sly and the Family Stone, has died at age 82 due to COPD and other health issues. He was known for his pioneering blend of funk, R&B, and soul, and his band's impactful music and flamboyant style. His family expressed sadness but celebrated his enduring musical legacy.
A key Phase 3 trial of Regeneron and Sanofi's COPD drug, itepekimab, failed to meet its primary endpoint, causing a significant drop in their stock prices, although one of the two trials showed a meaningful benefit. The companies are reviewing the data and consulting with regulators to determine next steps.
Regeneron Pharmaceuticals' stock dropped 17% after its late-stage trials for the COPD drug itepekimab only partially met goals, with one study showing some benefit and the other failing to meet primary endpoints, leading to concerns about the drug's future and impacting investor sentiment.
Regeneron Pharmaceuticals' stock dropped 12% after its COPD drug, developed with Sanofi, failed in a Phase 3 trial, with mixed results across two studies, potentially hindering approval efforts.
A new clinical trial has shown that the antibody drug benralizumab can significantly reduce asthma and COPD flare-ups, outperforming standard steroid treatments. Conducted by scientists in the UK, Australia, and Sweden, the trial found that patients receiving benralizumab experienced fewer treatment failures and hospital visits. Benralizumab, developed by AstraZeneca, targets eosinophils, white blood cells that contribute to asthma and COPD symptoms. The findings suggest benralizumab could become the first new treatment for these conditions in 50 years, pending further large-scale studies.