All articles tagged with #clinical studies
Genesis Therapeutics has raised $200 million in Series B financing, co-led by Andreessen Horowitz and an anonymous life science investor. The startup, which utilizes artificial intelligence to design small molecule drugs, plans to use the funds to further develop its AI technologies, expand its pipeline, and advance its first computer-generated drugs into clinical studies.
A systematic literature review published in JAMA Dermatology has found that biosimilar drugs are safe and effective in treating psoriasis. The analysis compared approved biological drugs with their biosimilar counterparts and found no clinically meaningful differences in efficacy and adverse events. Despite the potential advantages of biosimilars, such as easier access to innovative therapies and cost savings, doctors and patients have been slow to accept them. However, the future direction of biosimilars looks promising, with the potential for wider use outside of hospital reference centers. The study authors recommend considering biosimilars alongside originators to improve accessibility to biological treatments and suggest that switching from originator to biosimilar could be assessed to reduce treatment costs.
A new study has found that Semaglutide, a drug used to treat obesity and diabetes, significantly reduced alcohol consumption and relapses in alcohol-dependent rats by blocking alcohol-induced dopamine release in the brain's reward system. Clinical studies on humans are needed to confirm these findings, but the medication may be of most benefit to patients suffering from both overweight and alcohol dependence. Semaglutide is a long-acting substance that only needs to be taken once a week and is the first medication to act on the GLP-1 receptor that can be taken in tablet form.
Semaglutide, a medication used for type 2 diabetes and obesity, has shown potential as a treatment for alcohol dependence. The drug reduced alcohol relapse drinking and overall alcohol intake in rats by more than half. Semaglutide acts on the GLP-1 receptor and is taken in tablet form once a week. Clinical studies are needed to confirm the findings in humans, but the results offer promising insights into potential additional treatment options for alcohol dependence.
A new study from Lund University in Sweden highlights the challenges in clinical studies on osteoarthritis treatments. Patients with osteoarthritis often undergo variations in their level of pain, which can complicate the interpretation of results. The study found that much of the apparent treatment effect is just an illusion due to natural variation, and researchers need to take regression to the mean into account. To determine whether a treatment is effective or not, there must be an adequate control group that receives a placebo, and the treatment is randomly allocated.
A scoping review of randomized controlled trials published in the Journal of Ethnic Foods found that consuming fermented kimchi is associated with a wide range of health benefits, including improvements in blood glucose levels, prediabetic parameters, total cholesterol, LDL-C, HDL-C, serum lipid levels, skeletal muscle mass, and systolic blood pressure. Kimchi also alleviates symptoms of IBS and is possibly linked to inhibiting cancer cell growth in various cancers. However, more research is required to verify the conflicting results on the health benefits associated with kimchi.