The hypertension drug rilmenidine has been shown to extend lifespan and slow aging in worms and mice by mimicking caloric restriction effects, with potential implications for human health, pending further research.
The blood pressure drug rilmenidine has been shown to extend lifespan and slow aging in worms and mice by mimicking caloric restriction effects, with potential implications for human health and aging, pending further research.
A common blood pressure medication, rilmenidine, has been shown to extend lifespan in worms and mice by activating cellular pathways associated with caloric restriction, suggesting potential for anti-aging therapies in humans. The drug works by binding to imidazoline receptors, promoting autophagy and stress resistance, and could offer a practical alternative to calorie restriction for healthy aging.
The hypertension drug rilmenidine has been found to extend lifespan and slow aging in Caenorhabditis elegans worms by mimicking the effects of caloric restriction, a method known to prolong life in various animal models. This discovery suggests potential anti-aging benefits for humans, as rilmenidine is already widely prescribed with mild side effects. The study highlights the role of the nish-1 receptor in the drug's effectiveness, opening avenues for further research into its application in human aging. The findings were published in Aging Cell.
The hypertension drug rilmenidine has been found to slow down aging in worms, potentially offering a way to extend lifespan and improve health in humans. The drug mimics the effects of caloric restriction, which has been shown to increase lifespans in animals. In a study, worms treated with rilmenidine lived longer and showed improved health markers. Further tests on mice also revealed similar gene activity associated with caloric restriction. The drug's rare and mild side effects make it a promising candidate for anti-aging treatment, although more research is needed to determine its effectiveness in humans.
The hypertension drug rilmenidine has shown potential in slowing down aging and extending lifespan in worms, mimicking the effects of caloric restriction. In tests conducted on worms and mice, rilmenidine increased lifespan and improved health markers. The drug targets a biological signaling receptor called nish-1, which is crucial for its effectiveness. Rilmenidine is already widely prescribed, taken orally, and has relatively mild side effects. While further research is needed to determine its effectiveness in humans, these early findings offer promise for developing an anti-aging drug that could improve health in old age without the need for extreme calorie cutting.