Common high-blood-pressure drug hints at anti-aging potential in animals
A long-used hypertension medication, rilmenidine, extended lifespan in the worm C. elegans and induced youthful metabolic changes in mice, pointing to aging pathways that can be slowed with an existing drug. The study links the effect to the nish-1 receptor and autophagy, with older animals benefiting nearly as much as younger ones, and suggests early human trials could focus on biomarkers if safety remains favorable.