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Precision Psychiatry

All articles tagged with #precision psychiatry

health23 days ago•12 min saved

The Elusive Fit: Why Antidepressants Don’t Work for Everyone

Antidepressants have helped some people for decades, but research shows they often provide only modest relief overall, with no reliable way to predict who will benefit. The history traces from iproniazid and imipramine to SSRIs and beyond, while meta-analyses indicate small improvements over placebo and low remission rates for many drugs. Ketamine offers rapid relief for some with treatment-resistant depression, challenging the idea that depression is a simple chemical imbalance. Precision psychiatry aims to tailor treatments via blood tests and genetic or neural markers, but this approach is still years away from routine practice. The field continues to wrestle with what depression actually is and how to best help the millions affected.

via The Dispatch|

#antidepressants #depression #health

health2 years ago•1 min saved

"Revolutionary Blood Test Identifies Schizophrenia Risk and Optimal Treatments"

Scientists have developed a breakthrough blood test for schizophrenia, which can predict an individual's risk for developing the disorder and identify the most effective treatment by analyzing biomarkers in their blood. The test is expected to be commercially available later this year and could help match people to the right treatment from the beginning, particularly during the prime period of life when psychosis usually manifests. This new approach, part of emerging precision psychiatry, aims to provide early intervention and improve outcomes for individuals with schizophrenia.

via New York Post |

#biomarkers #blood-test #health

health2 years ago•5 min saved

"Revolutionary Blood Test Predicts and Guides Treatment for Schizophrenia"

Researchers at Indiana University have developed a groundbreaking blood test for schizophrenia that can objectively measure the severity and future risk of the disorder, allowing for personalized treatment plans. The test identifies specific biomarkers predictive of hallucinations, delusions, and future hospitalizations, and is expected to be available later this year through MindX Sciences. This innovation paves the way for advancements in precision psychiatry, potentially mitigating the disorder’s impact during critical periods of young adulthood.

via Neuroscience News|

#biomarkers #blood-test #health

health2 years ago•1 min saved

20-Year Catatonic Woman Awakens, Revolutionizes Psychiatry.

April Burrell, who was diagnosed with severe schizophrenia at 21, lived in a catatonic state in a psychiatric hospital for 20 years until a doctor discovered she also had lupus, which was attacking her brain. After targeted treatments, she woke up. Sander Markx, director of precision psychiatry at Columbia University, is now applying the breakthrough to other "lost souls" who might benefit from the insight. The research is reshaping the practice of psychiatry and the way many cases of mental illness are diagnosed and treated.

via Newser|

#health #lupus #medical-breakthrough

mental-health2 years ago•2 min saved

Avoiding Overfitting in Suicide Prediction Models

A new study highlights the dangers of overfitting in machine learning models used to predict suicidal ideation. The study argues that such models may be more likely to identify patterns in the data that are not actually related to suicidal ideation, leading to inaccurate predictions. The authors suggest that more research is needed to develop machine learning models that are better suited to predicting suicidal ideation and other mental health outcomes.

via Nature.com|

#machine-learning #mental-health #overfitting