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Pcsk9

All articles tagged with #pcsk9

Merck's PCSK9 Pill Shows Promise in Lowering Cholesterol to Injectable Levels

Originally Published 2 months ago — by The New York Times

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Source: The New York Times

Merck has developed a new pill called enlicitide that significantly reduces LDL cholesterol levels by blocking the PCSK9 protein, showing promising results in clinical trials with a 20% reduction in heart attack and stroke rates among high-risk patients, and offering a potentially more affordable alternative to existing injectable treatments.

Revolutionary Gene Therapy Halves Cholesterol Without Statins or Side Effects

Originally Published 2 months ago — by Science Daily

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Source: Science Daily

Researchers have developed a new therapy using polypurine hairpins to inhibit PCSK9, significantly reducing LDL cholesterol levels by nearly 50% without the side effects associated with statins, offering a promising alternative for managing hypercholesterolemia and preventing atherosclerosis.

The Far-Reaching Impact of Antibody Patent Disputes in Biotech

Originally Published 2 years ago — by Nature.com

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Source: Nature.com

A patent case before the US Supreme Court over rights to therapeutic antibodies that are used to treat high cholesterol could have far-reaching impacts on drug prices and technology. The decision could affect how specific patents of any ilk must be when they describe an invention, and how broad they can be. A win by Amgen could hinder the development of new medicines by restricting competition and discouraging the development of multiple therapeutic antibodies that bind to the same target.