
Swedish Study Links Forever Chemicals to Increased Risk of MS
A Swedish study analyzed blood from 907 newly diagnosed MS patients and 907 controls, measuring 24 PFAS compounds and seven PCB byproducts. Higher levels of PFAS (notably PFOS) and certain PCB byproducts were linked to roughly double the odds of an MS diagnosis, with the strongest risk when multiple PFAS/byproducts were present, indicating a chemical ‘toxic synergy.’ A gene variant associated with lower MS risk amplified the effect of PFOS exposure, suggesting gene–environment interactions. PFOS and hydroxylated PCBs can cross the blood–brain barrier and may trigger oxidative stress in the brain, potentially contributing to MS symptoms. The study underscores considering chemical mixtures, not single substances, in disease risk; it was published in Environment International.











