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Pancreatitis

All articles tagged with #pancreatitis

GLP-1 obesity drugs and pancreatitis: what the science actually shows
health9 days ago

GLP-1 obesity drugs and pancreatitis: what the science actually shows

Regulators in the UK and Brazil warned of a possible link between GLP-1 weight‑loss drugs and pancreatitis, but causality remains unclear. With millions using GLP-1 therapies for obesity and related conditions, reported pancreatitis cases and deaths are very rare relative to use (UK: 19 pancreatitis deaths since 2007 and about 1,300 related reports among ~1.6 million users; Brazil: 6 deaths and 145 pancreatitis cases since 2020). Meta-analyses yield mixed results—some show a small risk, others none—while a large real‑world study found no difference in pancreatitis between GLP‑1 users and non‑users with similar risk factors. Ongoing pharmacovigilance and rigorous studies are needed to distinguish true signals from background risk.

via Nature|
#clinical-trials#glp-1#health
UK warns of pancreatitis risk tied to Wegovy and Mounjaro GLP-1 drugs
health1 month ago

UK warns of pancreatitis risk tied to Wegovy and Mounjaro GLP-1 drugs

UK regulators have strengthened warnings that rare but severe pancreatitis, including necrotizing cases, has been reported in users of GLP-1/GIP obesity and diabetes drugs Wegovy and Mounjaro. The MHRA cites about 1,300 reports from 2007–Oct 2025, including 19 deaths and 24 necrotizing pancreatitis, across roughly 25 million packs dispensed. Doctors are advised to monitor patients and patients with severe persistent abdominal pain should seek medical care; clinicians should check for drug use, especially if purchased privately. Novo Nordisk and Eli Lilly say the overall benefit-risk remains positive and safety is being monitored.

via The Detroit News|
#glp-1#health#mounjaro
UK cautions on rare pancreatitis risk from GLP-1 weight-loss injections
health1 month ago

UK cautions on rare pancreatitis risk from GLP-1 weight-loss injections

The UK MHRA warns that GLP-1 obesity drugs like Wegovy, Mounjaro, and Ozempic carry a very small but real risk of acute pancreatitis. Users should seek immediate medical attention for severe, persistent stomach pain that may radiate to the back, especially with nausea or vomiting. While hundreds of pancreatitis reports exist, none are confirmed as caused by these medicines. About 1.6 million adults in the UK are estimated to have used GLP-1 products recently. Most patients benefit and are safe, but patients should discuss benefits and risks with their prescriber and report any suspected adverse effects.

via BBC|
#glp-1#health#mhra
MHRA Flags Rare Pancreatitis Risk From GLP-1 Weight-Loss Injectables
health1 month ago

MHRA Flags Rare Pancreatitis Risk From GLP-1 Weight-Loss Injectables

Britain’s MHRA warns that GLP-1 weight‑loss injections (semaglutide, tirzepatide) carry a small risk of pancreatitis. With about 1.6 million users in 2024–25, the Yellow Card scheme has logged 1,143 cases of pancreatitis (acute and chronic) and 17 deaths among GLP-1 users, most in 2025 (807 tirzepatide, 166 semaglutide). Fewer reports exist for liraglutide and dulaglutide. Patients should watch for severe, persistent abdominal pain with nausea and report suspected adverse reactions, while researchers use the Yellow Card Biobank to study genetic risk. Manufacturers reiterate safety and supervised use.

via The Guardian|
#glp-1#health#mhra
health7 months ago

Investigation into Fatal Side Effects of Weight Loss Drugs and Jabs

A UK investigation has been launched into potentially fatal side effects of GLP-1 weight loss drugs, such as Mounjaro and Ozempic, after nearly 400 reports of serious pancreatic issues and 10 deaths linked to pancreatitis. While these drugs are effective for weight loss and managing blood sugar, concerns about their safety, particularly regarding pancreatitis, are prompting regulatory scrutiny. Companies like Lilly and Novo Nordisk emphasize ongoing safety monitoring and the benefits of their medications.

via UNILAD|
#glp-1#health#mounjaro
UK investigates pancreas risks linked to weight loss and diabetes jabs
health8 months ago

UK investigates pancreas risks linked to weight loss and diabetes jabs

A study has been launched to investigate serious side effects, including pancreatitis, linked to weight loss drugs like Mounjaro, Ozempic, and Wegovy, after reports of hospitalizations and deaths. The research aims to identify genetic risk factors to improve safety and reduce adverse reactions, with data collection through the MHRA's Yellow Card scheme and saliva samples from affected patients.

via BBC|
#genomics-england#health#mhra
Survivor Shares Harrowing Battle with Flesh-Eating Bacteria
health1 year ago

Survivor Shares Harrowing Battle with Flesh-Eating Bacteria

Sam Lewis, a 38-year-old mother from Bournemouth, was nearly killed by a necrotizing pancreatitis caused by a gallstone blocking her bile duct. Initially misdiagnosed, her condition rapidly worsened, leading to a six-month hospital stay, during which she underwent surgery to remove half of her pancreas. Now living with chronic pancreatitis, Sam must adhere to a strict low-fat diet to prevent flare-ups, significantly altering her lifestyle and diet. Despite her challenges, she remains hopeful about enjoying future holidays.

via New York Post |
#diet#flesh-eating-bacteria#gallstone
Exploring the Benefits and Risks of Weight-Loss Jabs Like Ozempic
health1 year ago

Exploring the Benefits and Risks of Weight-Loss Jabs Like Ozempic

The death of a Scottish nurse after using the weight-loss drug tirzepatide, known as Mounjaro, has raised concerns about the safety of GLP-1 injections, which are increasingly used for obesity treatment. While generally considered safe, these drugs can cause severe side effects like pancreatitis, especially in individuals with certain risk factors such as obesity, diabetes, or a history of alcohol use. Experts advise careful monitoring and caution against purchasing these drugs from online pharmacies, which may not provide adequate medical oversight. Proper diet and medical supervision are crucial for minimizing risks.

via Daily Mail|
#glp-1-injections#health#online-pharmacies
"Unforeseen Risks: The Dark Side of Ozempic and Other Weight-Loss Drugs"
health-pharmaceuticals1 year ago

"Unforeseen Risks: The Dark Side of Ozempic and Other Weight-Loss Drugs"

Leading doctor Dr. Mark Hyman has warned about the potentially deadly side effects of the weight-loss drug Ozempic, including a 900 percent increased risk of pancreatitis and a 450 percent increased risk of bowel obstruction. The drug, which is given via injection, has been linked to over 100 deaths in the US and can cost up to $1,700 a month. While effective in weight loss, Dr. Hyman cautioned that it comes with significant medical and financial costs, and may require lifelong use to maintain results.

via Daily Mail|
#health-pharmaceuticals#ozempic#pancreatitis