Uniform DNA-encapsulating microgels mimic living cells.
Originally Published 2 years ago — by Phys.org
Researchers from Doshisha University in Japan have developed a one-step method for producing uniform gelatin-based cell mimetics called "microgels" that can be used to study cellular self-assembly. The microgels are created by generating domain structures comprising of polyethylene glycol (PEG) and gelatin, which are transformed into gel state by decreasing the temperature. The addition of DNA molecules to the gelatin-rich droplets spontaneously entrap them, giving rise to cell-mimicking microgels. The method proposed in the study may be useful for producing microgels for food, medicines, cosmetics, and other materials.