All articles tagged with #ldl reduction
An experimental gene therapy called VERVE-102, using base editing of the PCSK9 gene, shows promise in reducing LDL cholesterol in clinical trials, especially for those with familial hypercholesterolemia and premature coronary artery disease, with ongoing studies and potential for broad application.
A small clinical trial shows that a single infusion of the experimental gene-editing drug VERVE-102 can reduce LDL cholesterol levels by up to 69%, offering a potential permanent solution for high cholesterol through genetic modification, with further studies planned to confirm its safety and efficacy.
An early-stage trial of an experimental drug, VERVE 102, shows it can reduce bad cholesterol (LDL) by up to 69% with a single injection, potentially offering a lifelong treatment for cardiovascular risk factors. The drug, developed by Verve Therapeutics, uses gene editing to permanently turn off the PCSK9 gene, and has shown promising safety and efficacy results in a small group, prompting larger trials. Experts see this as a significant advancement in cholesterol management, especially for patients who are statin intolerant or have genetic dyslipidemias.
Low-dose statins are a class of medications used to manage high cholesterol and reduce the risk of heart attack, stroke, and death. They work by lowering LDL cholesterol and increasing HDL cholesterol. Common examples of low-dose statins include Zocor, generic pravastatin, and generic lovastatin. These medications are recommended for adults aged 40-75 who have at least one risk factor for cardiovascular disease. While low-dose statins are generally safe and well-tolerated, they can have side effects such as muscle pain. Pregnant and breastfeeding individuals should avoid statin use. Regular cholesterol monitoring, a healthy diet, and exercise are important for managing cholesterol levels.
Low-dose statins are a class of medications used to treat high cholesterol and reduce the risk of heart attack, stroke, and death. They work by lowering LDL cholesterol levels and increasing HDL cholesterol. Common low-dose statins include Zocor, generic pravastatin, and generic lovastatin. They are recommended for adults aged 40-75 who have at least one risk factor for cardiovascular disease. Low-dose statins are generally well-tolerated, but side effects may include muscle pain. They should be avoided during pregnancy and breastfeeding. Regular cholesterol monitoring, a healthy diet, and exercise are important for managing cholesterol levels.