All articles tagged with #genome regulation
New research suggests that the physical looping of DNA played a crucial role in the evolution of complex animals by enabling sophisticated gene regulation, which allowed cells to differentiate and form diverse tissues, marking a significant step from unicellular ancestors to multicellular organisms like cnidarians and ctenophores.
A study reveals that previously overlooked 'junk DNA,' specifically LINE-1 transposons, actively influences early brain development and may be linked to neurological diseases, challenging the notion that non-coding DNA is irrelevant.
Researchers have shed light on the mechanism by which DNA methylation represses gene transcription by identifying the MBD2 protein as a key reader of DNA methylation. This protein plays a crucial role in interpreting DNA methylation as a signal for transcriptional repression, particularly in regulating the expression of genes, transgenes, and transposable elements in plants. The study provides valuable insights into the intricate process of genome regulation and gene silencing.