Genetics And Molecular Biology News

"Exploring Forbidden Genomic Regions"

Researchers have shed light on the mechanism by which DNA methylation represses gene transcription by identifying the MBD2 protein as a key reader of DNA methylation. This protein plays a crucial role in interpreting DNA methylation as a signal for transcriptional repression, particularly in regulating the expression of genes, transgenes, and transposable elements in plants. The study provides valuable insights into the intricate process of genome regulation and gene silencing.