All articles tagged with #gene discovery
Scientists have discovered a gene linked to chronic pain, potentially paving the way for new, more effective treatments for the over 600 million people affected worldwide, as current understanding and therapies remain limited.
Howard Chang, a renowned genomic researcher and dermatologist, transitioned from academia and biotech startups to become Amgen's new CSO, focusing on genetic target discovery, extrachromosomal DNA, and technology development to advance drug discovery.
Researchers at The Australian National University have discovered a gene mutation, IKBKB, responsible for causing psoriasis and potentially leading to psoriatic arthritis. The mutation affects the function of immune cells, contributing to inflammation and disease onset. The findings offer hope for improved diagnosis and treatment, potentially leading to a cure for the conditions, which affect hundreds of thousands of Australians. Patients hope to break the stigma associated with these conditions and raise awareness of the challenges they face.
Researchers at Michigan State University have discovered a gene that causes potatoes to convert starch into sugar in cold weather, leading to less healthy chips and fries. By identifying the specific gene responsible for this process, they have uncovered a way to switch it off, potentially leading to the development of CIS-resistant potato genes that could produce healthier potato products. This discovery could have significant implications for food quality and health worldwide.
Researchers at Washington State University have discovered a gene in the testes that could lead to the development of a male contraceptive pill. Disabling the gene in mice caused infertility by changing sperm shape and movement. The gene, called ARRDC5, is expressed only in testicular tissue and is abundant in the testes of humans, mice, cattle, and pigs. The discovery could lead to a reversible male contraceptive pill that targets only sperm and has fewer side effects than interfering with male hormones. The researchers have filed a provisional patent for the male contraceptive pill based on this gene discovery.
Scientists at Cardiff University have discovered 92 more genes that could lead to life-changing treatment for Alzheimer's disease within the next 15 years. The defective genes change the way immune cells called microglia work, which can mistakenly kill off healthy brain cells, including synapses. Various therapies will be needed to combat the constellation of problems the disease represents. A drug may be available within ten years that would limit the suffering of Alzheimer's patients to initial mild confusion. A new computer program was also announced last year that could enable researchers to diagnose Alzheimer's disease much earlier.