All articles tagged with #eosinophils
New research identifies a brain-to-skin neural circuit that, under stress, activates eosinophils and fuels inflammation in atopic dermatitis, explaining how psychological stress worsens eczema in both mice and humans (51 participants showed higher stress and more inflammation).
A Science study shows a brain-to-skin neural circuit where stress activates sympathetic nerves that drive eosinophils, worsening eczema. In mice, reducing eosinophils diminished the stress-related flare, while in humans higher stress correlated with more inflammation and eosinophils, suggesting potential therapies that target this neuroimmune pathway to alleviate eczema symptoms.
A new study published in The Lancet Respiratory Medicine reveals that benralizumab, a monoclonal antibody, may be a breakthrough treatment for asthma and COPD flare-ups, offering a safer alternative to steroids like prednisolone. The trial showed that benralizumab significantly reduced treatment failure rates and improved patient outcomes, with fewer side effects compared to steroids. While benralizumab is already used for long-term asthma management, further phase 3 trials are needed to approve its use during flare-ups.