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Dipg

All articles tagged with #dipg

health1 month ago•29 min saved

Hope on Hold: DIPG Families Fight for Trials Amid U.S. Funding Cuts

A Guardian feature follows Izzy, a four-year-old with diffuse intrinsic pontine glioma (DIPG), and the families and doctors racing to find experimental treatments as the Trump era’s funding cuts cripple NIH support, shutter the Pediatric Brain Tumor Consortium, and suspend or delay dozens of clinical trials. The result is that progress in DIPG research stalls just as families face a last-hope window, turning access to new therapies into a bureaucratic and political obstacle. In the end, Izzy receives a reprieve when Stanford offers a CAR-T cell trial, a glimmer of hope amid a landscape of lost trials and dwindling resources.

via The Guardian|

#clinical-trials #dipg #health

health1 year ago•1 min saved

CAR-T Therapy Offers Hope for Aggressive Childhood Brain Tumors

A new study published in Nature reveals promising results for CAR-T therapy in treating diffuse intrinsic pontine gliomas (DIPG), a highly aggressive childhood brain tumor. Led by Michelle Monje-Deisseroth at Stanford University, the trial showed that four out of eleven patients experienced significant tumor reduction, with one patient remaining in complete remission 30 months post-treatment. Despite the high mortality rate, these findings offer hope for a condition previously deemed untreatable.

via STAT|

#brain-tumor #cancer-treatment #car-t-therapy

health1 year ago•4 min saved

"7-Year-Old Schoolboy Diagnosed with Inoperable Brain Tumour"

Seven-year-old Aubrey Rothery has been diagnosed with an inoperable and deadly brain tumour called diffuse midline glioma (DIPG), which typically kills most sufferers within a year. His parents initially dismissed his balance issues as a result of a growth spurt, but an MRI scan revealed the devastating diagnosis. Aubrey is currently undergoing radiotherapy at Bristol Children’s Hospital, and his parents are researching potential clinical trials for DIPG while fundraising for his treatments. DIPG symptoms include balance problems, weakness in limbs, speech and vision issues, and difficulty swallowing. The family is trying to remain hopeful while acknowledging the bleak prognosis associated with DIPG.

via Daily Mail|

#brain-tumour #childhood-cancer #dipg

health2 years ago•1 min saved

"13-Year-Old Belgian Boy First in the World to Beat Deadly Brain Cancer"

Lucas Jemeljanova, a 13-year-old boy from Belgium, has become the first person in the world to beat the deadly brain cancer DIPG, which typically has a very low survival rate. After being diagnosed at the age of six, Lucas participated in a clinical trial using the medication everolimus, which led to the gradual disappearance of his tumor. Now, seven years after being declared cancer-free, his case offers hope for others with this illness, although the reasons behind his recovery remain unclear.

via The News International|

#belgium #brain-cancer #dipg

health-and-medicine2 years ago•2 min saved

"World's First: 13-Year-Old Cured of Deadly Brain Tumor"

A 13-year-old boy has become the first person to be completely cured of a terminal brain tumor known as DIPG, thanks to a groundbreaking treatment involving the drug everolimus. The treatment, part of the BIOMEDE study, involved analyzing the molecular profile of each patient's tumor to determine the most suitable medication. The boy's tumor completely disappeared, and researchers are now working on a follow-up study and creating cancer organoids to test new drugs. While this breakthrough offers hope, researchers caution that an effective treatment for the illness is still a long way off.

via IFLScience|

#brain-tumor #cancer #dipg