All articles tagged with #brain atrophy
A study suggests that the Alzheimer's drug ALZ-801, a pill taken at home, may slow cognitive decline and brain atrophy in high-risk individuals, especially those with mild memory problems and the APOE4 gene, offering a potentially safer alternative to existing treatments.
A 6-year longitudinal neuroimaging study in Germany suggests that social isolation contributes to brain atrophy and cognitive decline in older adults. The study found that socially isolated individuals had smaller volumes in the hippocampus, reduced cortical thickness, and poorer cognitive functioning. These findings highlight the importance of promoting social connectedness, particularly among older adults, to potentially reduce the risk of dementia.
Estriol, a pregnancy hormone, has been found to reverse myelin breakdown in the brain's cortex, a primary area affected in multiple sclerosis (MS). MS results in inflammation that damages the myelin coating around nerve fibers in the brain's cortex, leading to disability worsening. However, the new study found that estriol not only prevented brain atrophy but also induced remyelination, suggesting it could repair MS-induced damage. This is the first study to identify a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.
A recent study has found that gray matter volume in various cortical areas decreases by an average of 5.25% per decade, with the rostral anterior cingulate cortex experiencing the most significant reduction. Men generally experience a higher rate of gray matter volume decrease than women, particularly in the cingulate lobe. The study's findings provide a normative reference for clinical conditions that involve abnormal brain atrophy, emphasizing the need for personalized and targeted strategies to manage age-related brain volume loss.