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Estriol

All articles tagged with #estriol

health2 years ago

Estriol and T-cell changes show promise for MS treatment.

Estriol, a hormone produced during pregnancy, has been found to reduce disease severity and promote myelin repair in the cortex, a key brain region affected in multiple sclerosis (MS), in a mouse model of the disease. The hormone has been in use for decades as a therapy to help manage symptoms of menopause and has a generally good safety profile. Based on these promising results, the scientists are calling for studies to examine the potential for this hormone as a treatment for women with MS.

health2 years ago

Estriol Treatment Shows Promise in Reversing Myelin Damage in Multiple Sclerosis.

Estriol, a pregnancy hormone, has been found to reverse myelin breakdown in the brain's cortex, a primary area affected in multiple sclerosis (MS). MS results in inflammation that damages the myelin coating around nerve fibers in the brain's cortex, leading to disability worsening. However, the new study found that estriol not only prevented brain atrophy but also induced remyelination, suggesting it could repair MS-induced damage. This is the first study to identify a treatment that could repair myelin in the cortex, undoing some of the damage caused by MS.