All articles tagged with #bmj medicine
A Washington University study of more than 333,000 U.S. veterans with type 2 diabetes found that continuous GLP-1 therapy reduced cardiovascular risk by about 18% after three years; stopping the medication for six months raised risk by 4%, after one year by 14%, and after two years by 22%, with restarting yielding only partial protection, highlighting the importance of long‑term use and accompanying lifestyle changes.
A large BMJ Medicine study using Veterans Health Administration records found that cardiovascular benefits from GLP-1 injections fade quickly after stopping the drugs: risk of heart attack, stroke and related events rises by about 4% at six months, 14% at one year, and 22% by the second year off therapy, approaching pre-treatment levels. The findings suggest ongoing GLP-1 treatment is needed to maintain heart benefits, with the advantage appearing to be partly weight-independent, as seen in related obesity trials.
A Harvard-led analysis of 111,373 people followed for over 30 years found that engaging in a variety of physical activities lowers overall death risk by about 19–20%, with walking alone offering the lowest risk; a mix of at least three activity types totaling around 20 Metabolic Equivalent Tasks (METs) per week yields the best results, though benefits plateau beyond roughly two hours of running or five hours of brisk walking weekly. The study, published in BMJ Medicine, is observational but supports encouraging diverse activity to extend lifespan.
A BMJ Medicine study of over 111,000 adults followed for more than 30 years found that those who did the widest variety of exercises—across cardio, strength, and everyday activities—had about a 19% lower risk of premature death compared with those who did less variety, with benefits seen at every activity level; experts say mixing workouts supports multiple health pathways, and any activity beats none, so aim for CDC guidance of about 150 minutes of moderate cardio per week plus two days of strength, while rotating exercises and adding daily tasks like gardening.
A BMJ Medicine analysis of more than 111,000 adults over 30 years found that people with the most varied workouts had a 19% lower risk of premature death than those with the least variety, regardless of total exercise time. Experts say mixing cardio, strength training, and everyday activities provides multiple physical and mental benefits, and while any activity helps, rotating routines may boost longevity.
A study published in BMJ Medicine suggests that regular use of fish oil supplements may increase the risk of stroke and atrial fibrillation in individuals without known heart conditions, while potentially reducing the risks for those with existing cardiovascular issues. The research followed over 400,000 people in the UK for 12 years and found a 13% higher risk of atrial fibrillation and a 5% heightened risk of stroke in individuals without known heart conditions who used fish oil supplements regularly. However, for patients with known heart disease, the supplements were associated with a 15% lower risk of atrial fibrillation. Further studies are needed to fully understand the relationship between fish oil supplements and heart disease events.