Tag

Antimicrobials

All articles tagged with #antimicrobials

science1 year ago

"Uncovering Soil Bacteria's Novel Antimicrobial Weaponry"

Researchers have discovered umbrella-shaped toxic protein particles secreted by soil bacteria Streptomyces to inhibit the growth of competing species, particularly others of their own genus. These large complexes, unlike small-molecule antibiotics, are highly specific in targeting bacteria and have evaded discovery for over a century. The discovery, published in Nature, sheds light on the bacteria's combative strategies and potential clinical applications, including combating antibiotic-resistant bacteria such as those causing tuberculosis and diphtheria.

health-and-science1 year ago

"Uncovering the Gut Bacteria's Impact on Vision Loss"

A study has found a surprising link between gut bacteria and inherited eye diseases, specifically those caused by a mutation in the CRB1 gene, which weakens the body's defenses and allows harmful bacteria to infiltrate the eye, leading to sight loss. Treating affected mice with antimicrobials prevented blindness, suggesting a potential new therapy for inherited eye diseases. The findings could transform the treatment landscape for CRB1-associated eye conditions and possibly extend to other eye diseases, offering hope for preventing deterioration in these blinding diseases.

health2 years ago

New Dual-Action Antibiotic Prevents C. Difficile Reinfections by Evolving Resistance.

Bacteria can develop resistance to antibiotics by adapting pumps to flush them out of their cells, according to a study by the Quadram Institute and University of East Anglia. The researchers exposed Salmonella bacteria to two different antibiotics and found that both antibiotics selected different mutations in a molecular pump that Salmonella uses to get rid of toxic compounds from inside its cells. The findings confirm a primary role for these pumps as the first line of defense against antimicrobials.