Tag

Antidepressant Effects

All articles tagged with #antidepressant effects

health-and-wellness1 year ago•3 min saved

"Uncovering the Mood-Boosting Power of Exercise for Depression"

A recent meta-analysis of 38 studies suggests that strength training can moderately reduce symptoms of depression, with factors such as duration, frequency, and specific parameters of the training sessions influencing its antidepressant effects. The study provides compelling evidence for the potential complementary role of strength training in combating depression, highlighting the importance of program design in maximizing its effectiveness. While the combination of strength training with other exercises did not significantly alter the outcome, the authors acknowledge certain limitations in the analysis and call for further research to explore potential variables that could influence outcomes.

via PsyPost|

#antidepressant-effects #depression #health-and-wellness

health-and-medicine1 year ago•4 min saved

"Unveiling Ketamine's Role in Mental Health Treatment: From Rave Drug to Depression Therapy"

A study published in Translational Psychiatry has revealed that the brain's opioid system plays a crucial role in mediating ketamine's rapid antidepressant effects. The research demonstrated that ketamine activates the endogenous opioid system in the prefrontal cortex, and disrupting this signaling blocks ketamine's antidepressant-like effects in rats. The study also found that ketamine treatment led to a significant increase in β-endorphin levels in the prefrontal cortex, and neutralizing β-endorphin action nullified the antidepressant-like effects of ketamine. These findings shed light on the underlying mechanisms of ketamine's antidepressant effects and suggest potential therapeutic targets for depression.

via PsyPost|

#antidepressant-effects #brain-mechanisms #depression

health2 years ago•5 min saved

"Microdosing LSD: A Promising Antidepressant Breakthrough"

A study from the University of Chicago suggests that low doses of LSD may have potential antidepressant effects in individuals with mild to moderate depressive symptoms. The study involved 39 healthy volunteers and found that participants with higher depression scores experienced significant increases in positive mood measures following LSD consumption, and reported a notable decrease in depression scores 48 hours after the LSD session. However, the study is limited by its small sample size and the need for further research to replicate and extend the findings to other samples.

via PsyPost|

#antidepressant-effects #depression #health

mental-health2 years ago•4 min saved

"Psilocybin's Potential as an Antidepressant Amplified by Emotional Breakthroughs and Ego Dissolution"

People who have used psilocybin hold strong expectations about its antidepressant effects, with those experiencing higher levels of mystical experiences, emotional breakthroughs, and ego dissolution holding greater expectations, according to new research. The study found that participants expected psilocybin-assisted therapy to have a substantial impact on reducing depressive symptoms, particularly related to hope and happiness. However, they anticipated fewer benefits for symptoms like motivation and sleep disturbances. The findings highlight the importance of expectancies in influencing treatment outcomes and suggest that psilocybin may be more effective in addressing cognitive and emotional symptoms of depression.

via PsyPost|

#antidepressant-effects #depression #expectations

mental-health2 years ago•6 min saved

"Ketamine's Impact on Depression: Rapid Neuroplasticity Changes and Treatment Response"

A study published in Translational Psychiatry has found that the response to ketamine treatment in patients with treatment-resistant depression is associated with rapid changes in neuroplasticity. Neuroplasticity refers to the brain's ability to change and reorganize its structure and function. The study used diffusion tensor imaging to measure neuroplasticity changes in depressed individuals before and after ketamine administration. The researchers found that reductions in mean diffusivity scores in specific brain regions predicted greater improvement in depression scores. However, there was an unexpected finding in the hippocampus, where higher mean diffusivity scores were associated with greater improvement in depression scores. The study suggests that neuroplasticity changes may play a key role in determining the antidepressant effects of ketamine in certain patients. Further research is needed to confirm and better understand these associations.

via PsyPost|

#antidepressant-effects #depression #ketamine